Anti-MPEG1 antibody (ab25146)
Key features and details
- Rabbit polyclonal to MPEG1
- Suitable for: WB
- Reacts with: Mouse, Rat
- Isotype: IgG
Overview
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Product name
Anti-MPEG1 antibody -
Description
Rabbit polyclonal to MPEG1 -
Host species
Rabbit -
Specificity
ab25146 recognises Mpg-1 (macrophage-specific gene, MSG, MPS1). -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Rat -
Immunogen
Recombinant full length protein corresponding to Rat MPEG1.
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Positive control
- LPS-stimulated RAW264.7 and rat spleen.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 6.50
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab25146 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use at an assay dependent concentration.
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Notes |
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WB
Use at an assay dependent concentration. |
Target
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Tissue specificity
Expressed in macrophages and peripheral blood monocytes. -
Sequence similarities
Contains 1 MACPF domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 17476 Mouse
- Entrez Gene: 64552 Rat
- SwissProt: A1L314 Mouse
- SwissProt: Q9WV57 Rat
- Unigene: 3999 Mouse
- Unigene: 162497 Rat
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Alternative names
- macrophage expressed 1 antibody
- Macrophage expressed gene 1 antibody
- Macrophage gene 1 protein antibody
see all
Datasheets and documents
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SDS download
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Datasheet download
References (4)
ab25146 has been referenced in 4 publications.
- Ebrahimnezhaddarzi S et al. Mpeg1 is not essential for antibacterial or antiviral immunity, but is implicated in antigen presentation. Immunol Cell Biol 100:529-546 (2022). PubMed: 35471730
- McCormack R et al. An Essential Role for Perforin-2 in Type I IFN Signaling. J Immunol 204:2242-2256 (2020). PubMed: 32161097
- McCormack RM et al. Enteric pathogens deploy cell cycle inhibiting factors to block the bactericidal activity of Perforin-2. Elife 4:N/A (2015). WB . PubMed: 26418746
- McCormack RM et al. Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria. Elife 4:N/A (2015). WB . PubMed: 26402460