Anti-Monoamine Oxidase B/MAOB antibody (ab88510)
Key features and details
- Mouse polyclonal to Monoamine Oxidase B/MAOB
- Suitable for: WB, IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Monoamine Oxidase B/MAOB antibody
See all Monoamine Oxidase B/MAOB primary antibodies -
Description
Mouse polyclonal to Monoamine Oxidase B/MAOB -
Host species
Mouse -
Tested applications
Suitable for: WB, IHC-P, ICC/IFmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length protein within Human Monoamine Oxidase B/MAOB. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: NP_000889.3 -
Positive control
- Human liver lysate. Human kidney tissue. heLa cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.40
Constituent: PBS
Storage buffer 1X PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab88510 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB | (1) | |
IHC-P | ||
ICC/IF |
Notes |
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IHC-P: Use at a concentration of 3 µg/ml.
WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: 59 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
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Function
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. -
Sequence similarities
Belongs to the flavin monoamine oxidase family. -
Cellular localization
Mitochondrion outer membrane. - Information by UniProt
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Database links
- Entrez Gene: 4129 Human
- Omim: 309860 Human
- SwissProt: P27338 Human
- Unigene: 654473 Human
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Alternative names
- Adrenalin oxidase antibody
- Amine oxidase (flavin containing) antibody
- Amine oxidase [flavin-containing] B antibody
see all
Images
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Anti-Monoamine Oxidase B/MAOB antibody (ab88510) at 1 µg/ml + Human liver lysate at 50 µg
Predicted band size: 59 kDa
Observed band size: 59 kDa -
All lanes : Anti-Monoamine Oxidase B/MAOB antibody (ab88510) at 1 µg/ml
Lane 1 : Transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 50 µg per lane.
Predicted band size: 59 kDa
Observed band size: 59 kDa -
Purified ab88510 at 3ug/ml staining Monoamine Oxidase B/MAOB in formalin-fixed, paraffin embedded Human kidney tissue.
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Immunofluorescent staining of Monoamine Oxidase B/MAOB in HeLa cells using purified ab88510 at 10ug/ml.
Protocols
Datasheets and documents
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Datasheet download
References (3)
ab88510 has been referenced in 3 publications.
- Weng L et al. Identification of Critical Genes and Proteins for Stent Restenosis Induced by Esophageal Benign Hyperplasia in Esophageal Cancer. Front Genet 11:563954 (2020). PubMed: 33391336
- Grouzmann E et al. Monoamine oxidase a down-regulation contributes to high metanephrine concentration in pheochromocytoma. J Clin Endocrinol Metab 97:2773-81 (2012). Human . PubMed: 22569243
- Peritore CS et al. Resveratrol attenuates L-DOPA-induced hydrogen peroxide toxicity in neuronal cells. Neuroreport 23:989-94 (2012). PubMed: 23114623