Anti-NPEPPS antibody (ab96066)
Key features and details
- Rabbit polyclonal to NPEPPS
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-NPEPPS antibody
See all NPEPPS primary antibodies -
Description
Rabbit polyclonal to NPEPPS -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Recombinant protein fragment containing a sequence corresponding to a region within amino acids 284-574 of Human NPEPPS
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Positive control
- A549, HeLa, HepG2 and HCT116 cell lysates
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab96066 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 103 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 103 kDa. |
Target
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Function
Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain. -
Tissue specificity
Detected in liver, epithelium of renal tubules, epithelium of small and large intestine, gastric epithelial cells, and alveoli of the lung (at protein level). -
Sequence similarities
Belongs to the peptidase M1 family. -
Cellular localization
Cytoplasm > cytosol. Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 9520 Human
- Entrez Gene: 19155 Mouse
- Entrez Gene: 50558 Rat
- Omim: 606793 Human
- SwissProt: P55786 Human
- SwissProt: Q11011 Mouse
- Unigene: 443837 Human
- Unigene: 29824 Mouse
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Alternative names
- AAP-S antibody
- Aminopeptidase puromycin sensitive antibody
- Cytosol alanyl aminopeptidase antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab96066 has not yet been referenced specifically in any publications.