Anti-NPY4R antibody - Extracellular domain (ab188915)
Key features and details
- Rabbit polyclonal to NPY4R - Extracellular domain
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-NPY4R antibody - Extracellular domain -
Description
Rabbit polyclonal to NPY4R - Extracellular domain -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins. -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Rabbit, Horse, Cow, Pig, Monkey, Gorilla -
Immunogen
Synthetic peptide corresponding to Human NPY4R (extracellular). 16 amino acid peptide from 2nd extracellular domain.
Database link: P50391 -
Positive control
- Human brain tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab188915 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
Use a concentration of 4 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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Notes |
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IHC-P
Use a concentration of 4 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
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Function
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PP, PP (2-36) and [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY and [Leu-31, Pro-34] NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13-36) > PP (31-36) > NPY free acid. -
Tissue specificity
Highest levels found in brain, coronary artery and ileum. Low levels in pancreas and kidney. Detected in colon and small intestine. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 505889 Cow
- Entrez Gene: 101141797 Gorilla
- Entrez Gene: 100052105 Horse
- Entrez Gene: 100996758 Human
- Entrez Gene: 5540 Human
- Entrez Gene: 397475 Pig
- Omim: 601790 Human
- SwissProt: P50391 Human
see all -
Alternative names
- MGC116897 antibody
- Neuropeptide Y receptor type 4 antibody
- NPY4 R antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab188915 has not yet been referenced specifically in any publications.