NVP-TAE684, ALK inhibitor (ab142082)
Key features and details
- Highly potent, selective ALK inhibitor
- CAS Number: 761439-42-3
- Purity: > 98%
- Soluble in DMSO
- Form / State: Solid
- Source: Synthetic
Overview
-
Product name
NVP-TAE684, ALK inhibitor -
Description
Highly potent, selective ALK inhibitor -
Purity
> 98% -
General notes
This product is manufactured by BioVision, an Abcam company and was previously called 1683 NVP-TAE684. 1683-5 is the same size as the 5 mg size of ab142082.
-
CAS Number
761439-42-3 -
Chemical structure
Properties
-
Chemical name
5-Chloro-2-N-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl] phenyl]-4-N-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine -
Molecular weight
614.20 -
Molecular formula
C30H40ClN7O3S -
PubChem identifier
16038120 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
CC(C)S(=O)(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCC(CC4)N5CCN (CC5)C)OC -
Source
Synthetic
-
Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
-
SDS download
-
Datasheet download
References (1)
ab142082 has been referenced in 1 publication.
- Nagashima M et al. Midkine-a Is Required for Cell Cycle Progression of Müller Glia during Neuronal Regeneration in the Vertebrate Retina. J Neurosci 40:1232-1247 (2020). PubMed: 31882403