Product nameAnti-OSCAR antibody
See all OSCAR primary antibodies
DescriptionRabbit polyclonal to OSCAR
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Synthetic peptide conjugated to KLH derived from within residues 250 to the C-terminus of Human OSCAR.
- This antibody gave a positive signal in the following human tissue lysates: Bone Marrow; Bone Tumor; Spleen.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab93817 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 30 kDa).|
FunctionRegulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation.
Sequence similaritiesBelongs to the leukocyte receptor complex/polymeric immunogobulin receptor (PIR/LRC) family.
Contains 2 Ig-like (immunoglobulin-like) domains.
Cellular localizationSecreted and Cell membrane.
- Information by UniProt
- hOSCAR antibody
- hOSCARM2 antibody
- hOSCARM3 antibody
All lanes : Anti-OSCAR antibody (ab93817) at 1 µg/ml
Lane 1 : Bone Marrow (Human) Tissue Lysate
Lane 2 : Bone Tumor (Human) Tissue Lysate
Lane 3 : Human spleen tissue lysate - total protein (ab29699)
Lysates/proteins at 10 µg per lane.
All lanes : Goat Anti-Mouse IgG H&L (HRP) preadsorbed (ab97040) at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 30 kDa
Observed band size: 28 kDa why is the actual band size different from the predicted?
Additional bands at: 200 kDa, 56 kDa, 65 kDa. We are unsure as to the identity of these extra bands.
Exposure time: 20 minutes
This product has been referenced in:
- Nagy E et al. Interferon-? Released by Activated CD8+ T Lymphocytes Impairs the Calcium Resorption Potential of Osteoclasts in Calcified Human Aortic Valves. Am J Pathol 187:1413-1425 (2017). IHC-Fr . Read more (PubMed: 28431214) »
- Song J et al. a-Linolenic Acid Inhibits Receptor Activator of NF-?B Ligand Induced (RANKL-Induced) Osteoclastogenesis and Prevents Inflammatory Bone Loss via Downregulation of Nuclear Factor-KappaB-Inducible Nitric Oxide Synthases (NF-?B-iNOS) Signaling Pathways. Med Sci Monit 23:5056-5069 (2017). Read more (PubMed: 29061958) »