Anti-Oligodendrocyte Specific Protein antibody - Oligodendrocyte Marker (ab53041)
Key features and details
- Rabbit polyclonal to Oligodendrocyte Specific Protein - Oligodendrocyte Marker
- Suitable for: ICC, WB
- Reacts with: Mouse, Rat
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
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Overview
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Product name
Anti-Oligodendrocyte Specific Protein antibody - Oligodendrocyte Marker
See all Oligodendrocyte Specific Protein primary antibodies -
Description
Rabbit polyclonal to Oligodendrocyte Specific Protein - Oligodendrocyte Marker -
Host species
Rabbit -
Specificity
Whilst ab53041 has been generated using synthetic peptide corresponding to human Oligodendrocyte protein (C-terminal), the antibody has only been validated for use in mouse.
Detects endogenous levels of total Oligodendrocyte Specific Protein.
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Tested applications
Suitable for: ICC, WBmore details -
Species reactivity
Reacts with: Mouse, Rat
Predicted to work with: Human -
Immunogen
Synthetic peptide corresponding to Human Oligodendrocyte Specific Protein (C terminal).
Database link: O75508 -
Positive control
- WB: Mouse brain extract.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 0.87% Sodium chloride, PBS
Without Mg+2 and Ca+2 -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab53041 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ICC | (1) |
1/200.
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WB | (1) |
1/500 - 1/1000. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa).
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Notes |
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ICC
1/200. |
WB
1/500 - 1/1000. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa). |
Target
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Function
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. -
Sequence similarities
Belongs to the claudin family. -
Cellular localization
Cell junction > tight junction. Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 5010 Human
- Entrez Gene: 18417 Mouse
- Entrez Gene: 84588 Rat
- Omim: 601326 Human
- SwissProt: O75508 Human
- SwissProt: Q60771 Mouse
- SwissProt: Q99P82 Rat
- Unigene: 31595 Human
see all -
Alternative names
- Claudin 11 antibody
- Claudin-11 antibody
- CLD11_HUMAN antibody
see all
Images
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All lanes : Anti-Oligodendrocyte Specific Protein antibody - Oligodendrocyte Marker (ab53041) at 1/500 dilution
Lane 1 : Mouse brain extract
Lane 2 : Mouse brain extract with peptide
Predicted band size: 22 kDa
Observed band size: 22 kDaSecondary antibody - anti-rabbit HRP (ab6721)
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (70)
ab53041 has been referenced in 70 publications.
- Filiou MD et al. Multi-Omics Analysis Reveals Myelin, Presynaptic and Nicotinate Alterations in the Hippocampus of G72/G30 Transgenic Mice. J Pers Med 12:N/A (2022). PubMed: 35207732
- Gargareta VI et al. Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice. Elife 11:N/A (2022). PubMed: 35543322
- Webb SM et al. The incubation of cocaine craving is dissociated from changes in glial cell markers within prefrontal cortex and nucleus accumbens of rats. Addict Neurosci 3:N/A (2022). PubMed: 36034166
- Hosoya M et al. Development of the stria vascularis in the common marmoset, a primate model. Sci Rep 12:19811 (2022). PubMed: 36396805
- Maier-Begandt D et al. A venous-specific purinergic signaling cascade initiated by Pannexin 1 regulates TNFα-induced increases in endothelial permeability. Sci Signal 14:N/A (2021). PubMed: 33653920