Anti-PNGase antibody (ab73984)
Key features and details
- Rabbit polyclonal to PNGase
- Suitable for: ICC, WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-PNGase antibody
See all PNGase primary antibodies -
Description
Rabbit polyclonal to PNGase -
Host species
Rabbit -
Tested applications
Suitable for: ICC, WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide within Human PNGase aa 100-200 (internal sequence). The exact sequence is proprietary.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Constituent: Whole serum -
Concentration information loading...
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Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab73984 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ICC |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration.
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Notes |
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ICC
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
Target
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Relevance
NGLY1 is a highly conserved enzyme that catalyzes deglycosylation of misfolded N-linked glycoproteins by cleaving the glycan chain before the proteins are degraded by the proteasome (Zhou et al., 2006). -
Cellular localization
Cytoplasm -
Database links
- Entrez Gene: 55768 Human
- Entrez Gene: 59007 Mouse
- Entrez Gene: 361014 Rat
- Omim: 610661 Human
- SwissProt: Q96IV0 Human
- SwissProt: Q9JI78 Mouse
- SwissProt: Q5XI55 Rat
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Alternative names
- CDG1V antibody
- hPNGase antibody
- N glycanase 1 antibody
see all
Protocols
Datasheets and documents
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Datasheet download
References (1)
ab73984 has been referenced in 1 publication.
- Wu KX et al. Human genome-wide RNAi screen reveals host factors required for enterovirus 71 replication. Nat Commun 7:13150 (2016). PubMed: 27748395