Overview

  • Product name

  • Description

    Rabbit polyclonal to PNGase
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ICCmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide within Human PNGase aa 100-200 (internal sequence). The exact sequence is proprietary.

  • General notes

    Protein previously known as NGLY1.

Properties

Applications

Our Abpromise guarantee covers the use of ab73984 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/200 - 1/2000. Predicted molecular weight: 74 kDa.
ICC Use at an assay dependent dilution.

Target

  • Relevance

    NGLY1 is a highly conserved enzyme that catalyzes deglycosylation of misfolded N-linked glycoproteins by cleaving the glycan chain before the proteins are degraded by the proteasome (Zhou et al., 2006).
  • Cellular localization

    Cytoplasm
  • Database links

  • Alternative names

    • CDG1V antibody
    • hPNGase antibody
    • N glycanase 1 antibody
    • NGLY 1 antibody
    • Peptide N(4) (N acetyl beta glucosaminyl asparagine amidase antibody
    • Peptide:N glycanase antibody
    • PNG1 antibody
    • PNGase antibody
    see all

References

This product has been referenced in:

  • Wu KX  et al. Human genome-wide RNAi screen reveals host factors required for enterovirus 71 replication. Nat Commun 7:13150 (2016). Read more (PubMed: 27748395) »
See 1 Publication for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab73984.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up