Anti-PPP1R15B antibody (ab76785)
Key features and details
- Rabbit polyclonal to PPP1R15B
- Suitable for: IHC-Fr, WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-PPP1R15B antibody
See all PPP1R15B primary antibodies -
Description
Rabbit polyclonal to PPP1R15B -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Fr, WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide corresponding to Human PPP1R15B (C terminal).
Database link: Q5SWA1 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Constituent: Whole serum -
Concentration information loading...
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Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab76785 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-Fr |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration.
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Notes |
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IHC-Fr
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
Target
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Relevance
PPP1R15B belongs to the PPP1R15 family. It maintains low levels of EIF2S1 phosphorylation in un-stressed cells by promoting its dephosphorylation by PP1. The phosphatase activity of the PPP1R15B-PP1 complex toward EIF2S1 is specifically inhibited by Salubrinal, a drug that protects cells from endoplasmic reticulum stress. -
Database links
- Entrez Gene: 84919 Human
- Entrez Gene: 108954 Mouse
- Entrez Gene: 304799 Rat
- Omim: 613257 Human
- SwissProt: Q5SWA1 Human
- SwissProt: Q8BFW3 Mouse
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Alternative names
- CREP antibody
- FLJ14744 antibody
- PPP1R15B antibody
see all
Protocols
Datasheets and documents
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Datasheet download
References (0)
ab76785 has not yet been referenced specifically in any publications.