Anti-Pan2 antibody (ab222810)
Key features and details
- Rabbit polyclonal to Pan2
- Suitable for: ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Pan2 antibody
See all Pan2 primary antibodies -
Description
Rabbit polyclonal to Pan2 -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IF, IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment corresponding to Human Pan2 aa 628-908.
Database link: Q504Q3 -
Positive control
- IHC-P: Human liver tissue. ICC/IF: HepG2 (human liver hepatocellular carcinoma cell line) cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
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Purity
Protein G purified -
Purification notes
Purity >95%. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab222810 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
ICC/IF |
1/50 - 1/200.
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IHC-P |
1/20 - 1/200.
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Notes |
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ICC/IF
1/50 - 1/200. |
IHC-P
1/20 - 1/200. |
Target
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Function
Functions in cytoplasmic mRNA decay. As part of the Pan nuclease complex, shortens poly(A) tails of RNA when the poly(A) stretch is bound by polyadenylate-binding protein. -
Sequence similarities
Belongs to the peptidase C19 family. PAN2 subfamily.
Contains 1 exonuclease domain. -
Cellular localization
Cytoplasm. Nucleus. Shuttles between nucleus and cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 9924 Human
- SwissProt: Q504Q3 Human
- Unigene: 273397 Human
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Alternative names
- hPan2 antibody
- Inactive ubiquitin carboxyl terminal hydrolase 52 antibody
- Inactive ubiquitin carboxyl-terminal hydrolase 52 antibody
see all
Images
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Paraffin-embedded human liver tissue stained for Pan2 using ab222810 at 1/100 dilution in immunohistochemical analysis.
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HepG2 (human liver hepatocellular carcinoma cell line) cells stained for Pan2 (green) using ab222810 at 1/100 dilution in ICC/IF, followed by Alexa Fluor 488® conjugated Goat Anti-Rabbit IgG (H+L).
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab222810 has not yet been referenced specifically in any publications.