Recombinant Human ARMS2 protein (denatured) (ab174457)
Key features and details
- Expression system: Escherichia coli
- Purity: > 85% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE
Description
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Product name
Recombinant Human ARMS2 protein (denatured) -
Purity
> 85 % SDS-PAGE. -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MGSSHHHHHHSSGLVPRGSHMGSMLRLYPGPMVTEAEGKGGPEMASLSSS VVPVSFISTLRESVLDPGVGGEGASDKQRSKLSLSHSMIPAAKIHTELCL PAFFSPAGTQRRFQQPQHHLTLSIIHTAAR -
Predicted molecular weight
14 kDa including tags -
Amino acids
1 to 107 -
Tags
His tag N-Terminus -
Additional sequence information
NCBI Accession No.: NP_001093137
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Description
Recombinant Human ARMS2 protein
Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab174457 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.32% Tris HCl, 2.4% Urea, 10% Glycerol (glycerin, glycerine)
General Info
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Alternative names
- Age related maculopathy susceptibility 2
- Age related maculopathy susceptibility protein 2 mitochondrial
- ARMD8
see all -
Relevance
ARMS2 is thought to play a role in diseases in the elderly. Mutations in this gene have been associated with age-related macular degeneration (ARMD). ARMD is the most common cause of irreversible vision loss. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid (known as drusen) that lie beneath the retinal pigment epithelium and within an elastin containing structure known as Bruch's membrane. ARMD is likely to be a mechanistically heterogeneous group of disorders, and the specific disease mechanisms that underlie the vast majority of cases are currently unknown. However, studies have suggested that both genetic and environmental factors may be implicated. -
Cellular localization
Cytoplasmic
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab174457 has not yet been referenced specifically in any publications.