Recombinant Human C Reactive Protein (denatured) (ab111647)

Submit an Abreview Q&A (2)Specific References (2)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
      P02741
    • Species
      Human
    • Sequence
      MQTDMSRKAFVFPKESDTSYVSLKAPLTKPLKAFTVCLHFYTELSSTRGY SIFSYATKRQDNEILIFWSKDIGYSFTVGGSEILFEVPEVTVAPVHICTS WESASGIVEFWVDGKPRVRKSLKKGYTVGAEASIILGQEQDSFGGNFEGS QSLVGDIGNVNMWDFVLSPDEINTIYLGGPFSPNVLNWRALKYEVQGEVF TKPQLWP
    • Molecular weight
      23 kDa including tags
    • Amino acids
      19 to 244

Specifications

Our Abpromise guarantee covers the use of ab111647 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 90 % SDS-PAGE.

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 20% Glycerol, 12.01% Urea
    Note: Contains 67% Tris-HCl buffer.

General Info

  • Alternative names
    • Pentraxin 1, short
    • C reactive protein
    • C reactive protein pentraxin related
    • C-reactive protein(1-205)
    • CRP
    • CRP_HUMAN
    • MGC88244
    • Pentraxin 1
    • PTX 1
    • PTX1
    see all
  • Function
    Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
  • Tissue specificity
    Found in plasma.
  • Sequence similarities
    Belongs to the pentaxin family.
    Contains 1 pentaxin domain.
  • Cellular localization
    Secreted.
  • Information by UniProt

Images

  • SDS-PAGE - Recombinant Human C Reactive Protein (denatured) (ab111647)
    SDS-PAGE - Recombinant Human C Reactive Protein (denatured) (ab111647)
    15% SDS-PAGE analysis of ab111647 (3 µg)

References

This product has been referenced in:
  • Fang Z  et al. High-Throughput Study of the Effects of Celastrol on Activated Fibroblast-Like Synoviocytes from Patients with Rheumatoid Arthritis. Genes (Basel) 8:N/A (2017). Read more (PubMed: 28878153) »
  • Ko JA & Lim HB Metal-doped inorganic nanoparticles for multiplex detection of biomarkers by a sandwich-type ICP-MS immunoassay. Anal Chim Acta 938:1-6 (2016). Read more (PubMed: 27619081) »

See all 2 Publications for this product

Publishing research using ab111647? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

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2 reviews or Q&A

10
Votes: Highest First

Thanks alot. However is there something missing in this number: 45045 5 M-1 cm- a decimal or something. Please clarify ASAP.

Thank you for your reply. I mistakenly typed in another '5' in previous value I gave you. Therefore the number should be 45045M-1 cm-1. Apologies for any confusion that it caused. Also just to reconfirm that you should have received 100ug of protein in...

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I have bought ab111647 (100ul at 1 mg/ml). After dialysis I wanted to check the concentration so I used an extinction coefficient of 1.75 and the absorbance I got after 5 fold dilution was 0.5. If I calculated correctly the initial concentration seems ...

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Thank you for contacting Abcam. I can confirm that there should have been 100ug protein in the vial that you received (you may have gotten a little more, but not that much). As for you extinction coefficient, using the http://web.expasy.org/cgi-bin/pro...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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