The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% SDS-PAGE. purified by using conventional chromatography techniques
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.242% Tris, 10% Glycerol
18 kDa phosphoprotein
Cofilin 1 non muscle
Cofilin non muscle isoform
epididymis secretory protein Li 15
Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.
Widely distributed in various tissues.
Belongs to the actin-binding proteins ADF family. Contains 1 ADF-H domain.
Phosphorylated on Ser-3 in resting cells.
Nucleus matrix. Cytoplasm > cytoskeleton. Almost completely in nucleus in cells exposed to heat shock or 10% dimethyl sulfoxide.