Recombinant human Neuritin protein (ab69755)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies
Description
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Product name
Recombinant human Neuritin protein -
Biological activity
Determined by a cell proliferation using rat C6 cells. The ED50 for this effect is 20.0-30.0 ng/mL.
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Purity
> 98 % SDS-PAGE.
Purity is greater than 98% by SDS-PAGE and HPLC analyses. Endotoxin level is <0.100 ng/µg. -
Endotoxin level
< 1.000 Eu/µg -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
M-AGKCDAVFK GFSDCLLKLG DSMANYPQGL DDKTNIKTVC TYWEDFHSCT VTALTDCQEG AKDMWDKLRK ESKNLNIQGS LFELCGSGN -
Predicted molecular weight
19 kDa -
Amino acids
28 to 115
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab69755 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
Functional Studies
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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ReconstitutionReconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8oC for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20oC to -80oC.
General Info
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Alternative names
- Neuritin
- Neuritin 1
- NRN
see all -
Function
Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells. -
Sequence similarities
Belongs to the neuritin family. -
Cellular localization
Cell membrane. Cell junction > synapse. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (2)
ab69755 has been referenced in 2 publications.
- Gonzalez-Figueroa P et al. Follicular regulatory T cells produce neuritin to regulate B cells. Cell 184:1775-1789.e19 (2021). PubMed: 33711260
- Sato H et al. Thalamus-derived molecules promote survival and dendritic growth of developing cortical neurons. J Neurosci 32:15388-402 (2012). PubMed: 23115177