HRP Anti-Respiratory Syncytial Virus antibody (ab20686)
Key features and details
- HRP Goat polyclonal to Respiratory Syncytial Virus
- Suitable for: IHC-P, ELISA, Neutralising
- Reacts with: Respiratory syncytial virus
- Conjugation: HRP
- Isotype: IgG
Overview
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Product name
HRP Anti-Respiratory Syncytial Virus antibody
See all Respiratory Syncytial Virus primary antibodies -
Description
HRP Goat polyclonal to Respiratory Syncytial Virus -
Host species
Goat -
Conjugation
HRP -
Tested applications
Suitable for: IHC-P, ELISA, Neutralisingmore details -
Species reactivity
Reacts with: Respiratory syncytial virus -
Immunogen
Tissue, cells or virus corresponding to Respiratory Syncytial Virus. Human Respiratory Syncytial Virus isolate.
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General notes
Covalently coupled to a highly purified preparation of Horseradish Peroxidase (RZ>3). Care is taken to ensure adequate conjugation while preserving maximum enzyme activity. Free enzyme is removed.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
Preservative: 0.002% Thimerosal (merthiolate)
Constituents: PBS, 1% BSA -
Concentration information loading...
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Purity
IgG fraction -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab20686 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use at an assay dependent dilution.
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|
ELISA |
1/200 - 1/1000.
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|
Neutralising |
1/256.
|
Notes |
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IHC-P
Use at an assay dependent dilution. |
ELISA
1/200 - 1/1000. |
Neutralising
1/256. |
Target
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Relevance
Respiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. RSV infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. RSV is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, results in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells. -
Cellular localization
Virion. Host cytoplasm -
Database links
- Entrez Gene: 2829063 Respiratory syncytial virus
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Alternative names
- RS virus antibody
- RSV antibody
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab20686 has been referenced in 3 publications.
- Pavot V et al. A novel vaccine adjuvant based on straight polyacrylate potentiates vaccine-induced humoral and cellular immunity in cynomolgus macaques. Hum Vaccin Immunother 17:2336-2348 (2021). PubMed: 33427044
- Jones HG et al. Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies. PLoS Pathog 14:e1006935 (2018). PubMed: 29509814
- Groppo R et al. Effect of genetic background and delivery route on the preclinical properties of a live attenuated RSV vaccine. PLoS One 13:e0199452 (2018). PubMed: 29920563