Anti-SLITRK5 antibody (ab67309)
Key features and details
- Rabbit polyclonal to SLITRK5
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-SLITRK5 antibody -
Description
Rabbit polyclonal to SLITRK5 -
Host species
Rabbit -
Specificity
ab67309 is predicted to have no cross-reactivity to other SLITRK proteins. -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- WB: 3T3 cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab67309 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 160 kDa (predicted molecular weight: 107 kDa).
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Notes |
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WB
Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 160 kDa (predicted molecular weight: 107 kDa). |
Target
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Relevance
SLIT and NTRK-like family 5 (SLITRK5) is a member a protein family consisting of six homologous transmembrane proteins (SLITRK1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of SLITRK proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Like every other SLITRK protein except SLITRK1, overexpression of SLITRK5 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth. -
Cellular localization
Membrane; Single-pass type I membrane protein. -
Database links
- Entrez Gene: 75409 Mouse
- SwissProt: Q810B7 Mouse
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Alternative names
- bA364G4.2 antibody
- KIAA0918 antibody
- Leucine rich repeat containing 11 antibody
see all
Images
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All lanes : Anti-SLITRK5 antibody (ab67309) at 1 µg/ml
Lane 1 : 3T3 cell lysate with no blocking peptide
Lane 2 : 3T3 cell lysate with blocking peptide
Lysates/proteins at 15 µg per lane.
Predicted band size: 107 kDa
Observed band size: 160 kDa why is the actual band size different from the predicted?
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab67309 has been referenced in 1 publication.
- Kogan-Sakin I et al. Mutant p53(R175H) upregulates Twist1 expression and promotes epithelial-mesenchymal transition in immortalized prostate cells. Cell Death Differ : (2010). PubMed: 20689556