Anti-MIEF2 antibody (ab101350)
Key features and details
- Rabbit polyclonal to MIEF2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-MIEF2 antibody -
Description
Rabbit polyclonal to MIEF2 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment corresponding to Human MIEF2 aa 299-441. (AAH14973)
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Positive control
- 293T, A431, Jurkat and Raji whole cell lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab101350 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | (1) |
1/500 - 1/3000. Predicted molecular weight: 49 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 49 kDa. |
Target
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Function
Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity. -
Tissue specificity
Expressed in all tissues tested with highest expression in heart and skeletal muscle. -
Sequence similarities
Belongs to the MID49/MID51 family. -
Cellular localization
Mitochondrion outer membrane. Colocalizes with DNM1L at mitochondrial membrane. Forms foci and rings around mitochondria. - Information by UniProt
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Database links
- Entrez Gene: 125170 Human
- SwissProt: Q96C03 Human
- Unigene: 655555 Human
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Alternative names
- MGC23130 antibody
- MID49 antibody
- MID49_HUMAN antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab101350 has been referenced in 2 publications.
- Das R et al. CMT2A-linked mitochondrial hyperfusion-driving mutant MFN2 perturbs ER-mitochondrial associations and Ca2+ homeostasis. Biol Cell 114:309-319 (2022). PubMed: 35924634
- Li H et al. Mst1 deletion attenuates renal ischaemia-reperfusion injury: The role of microtubule cytoskeleton dynamics, mitochondrial fission and the GSK3ß-p53 signalling pathway. Redox Biol 20:261-274 (2019). PubMed: 30384260