Anti-SQRDL antibody (ab71978)
Key features and details
- Mouse polyclonal to SQRDL
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-SQRDL antibody
See all SQRDL primary antibodies -
Description
Mouse polyclonal to SQRDL -
Host species
Mouse -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length protein within Human SQRDL. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab71978 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/1000. Predicted molecular weight: 50 kDa.
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Notes |
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WB
1/500 - 1/1000. Predicted molecular weight: 50 kDa. |
Target
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Function
Catalyzes the oxidation of hydrogen sulfide, with the help of a quinone. -
Sequence similarities
Belongs to the SQRD family. -
Cellular localization
Mitochondrion. - Information by UniProt
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Database links
- Entrez Gene: 58472 Human
- SwissProt: Q9Y6N5 Human
- Unigene: 511251 Human
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Alternative names
- 0610039J17Rik antibody
- 4930557M22Rik antibody
- CGI 44 antibody
see all
Images
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All lanes : Anti-SQRDL antibody (ab71978) at 1/500 dilution
Lane 1 : SQRDL transfected 293T cell lysate
Lane 2 : Non transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat anti-mouse IgG (H&L)-HRP conjugate at 1/2500 dilution
Predicted band size: 50 kDa
Observed band size: 40 kDa why is the actual band size different from the predicted?
Datasheets and documents
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Datasheet download
References (4)
ab71978 has been referenced in 4 publications.
- Barayeu U et al. Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals. Nat Chem Biol 19:28-37 (2023). PubMed: 36109647
- Sanchez-Aranguren LC et al. Bioenergetic effects of hydrogen sulfide suppress soluble Flt-1 and soluble endoglin in cystathionine gamma-lyase compromised endothelial cells. Sci Rep 10:15810 (2020). PubMed: 32978411
- Ezerina D et al. N-Acetyl Cysteine Functions as a Fast-Acting Antioxidant by Triggering Intracellular H2S and Sulfane Sulfur Production. Cell Chem Biol 25:447-459.e4 (2018). PubMed: 29429900
- Zhang S et al. hsa-miR-29c-3p regulates biological function of colorectal cancer by targeting SPARC. Oncotarget 8:104508-104524 (2017). PubMed: 29262657