Anti-Striatin antibody (ab193000)
Key features and details
- Rabbit polyclonal to Striatin
- Suitable for: WB, IP
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-Striatin antibody
See all Striatin primary antibodies -
Description
Rabbit polyclonal to Striatin -
Host species
Rabbit -
Tested applications
Suitable for: WB, IPmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Chimpanzee, Gorilla, Orangutan -
Immunogen
Synthetic peptide within Human Striatin aa 250-350. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements. (NP_003153.2).
Database link: O43815 -
Positive control
- HeLa, 293T, Jurkat, TCMK-1 and NIH 3T3 whole cell lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7
Preservative: 0.09% Sodium azide
Constituent: 99% Tris citrate/phosphate
pH 7 to 8 -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
ab193000 was affinity purified using an epitope specific to Striatin immobilized on solid support. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab193000 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/2000 - 1/10000. Predicted molecular weight: 86 kDa.
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IP |
Use at 2-10 µg/mg of lysate.
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Notes |
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WB
1/2000 - 1/10000. Predicted molecular weight: 86 kDa. |
IP
Use at 2-10 µg/mg of lysate. |
Target
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Function
Calmodulin-binding protein which may function as scaffolding or signaling protein and may play a role in dendritic Ca(2+) signaling. -
Tissue specificity
Preferentially expressed in brain. -
Sequence similarities
Belongs to the WD repeat striatin family.
Contains 6 WD repeats. -
Cellular localization
Cytoplasm. Membrane. Cell projection, dendritic spine. CTTNBP2-binding may regulate dendritic spine distribution. - Information by UniProt
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Database links
- Entrez Gene: 470350 Chimpanzee
- Entrez Gene: 101132121 Gorilla
- Entrez Gene: 6801 Human
- Entrez Gene: 268980 Mouse
- Entrez Gene: 100443814 Orangutan
- SwissProt: O43815 Human
- SwissProt: O55106 Mouse
- Unigene: 127486 Human
see all -
Alternative names
- MGC125642 antibody
- SG2NA antibody
- Striatin antibody
see all
Images
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All lanes : Anti-Striatin antibody (ab193000) at 0.1 µg/ml
Lane 1 : HeLa whole cell lysate
Lane 2 : 293T whole cell lysate
Lane 3 : Jurkat whole cell lysate
Lane 4 : TCMK-1 whole cell lysate
Lane 5 : NIH 3T3 whole cell lysate
Lysates/proteins at 50 µg per lane.
Developed using the ECL technique.
Predicted band size: 86 kDa
Exposure time: 30 secondsLysates prepared using NETN lysis buffer.
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Detection of Striatin in immunoprecipitates of 293T whole cell lysate (prepared using NETN lysis buffer; 1 mg for IP, 20% of IP loaded) using ab193000 at 6 µg/mg lysate for IP and at 1 µg/ml for subsequent Western blot detection (Lane 1). Lane 2 represents control IgG IP.
Detection: Chemiluminescence with an exposure time of 30 seconds.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab193000 has been referenced in 2 publications.
- Tang Y et al. Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer. Cancer Cell 38:115-128.e9 (2020). PubMed: 32589942
- Zou Y et al. Characteristic expression and significance of CCL19 in different tissue types in chronic rhinosinusitis. Exp Ther Med 11:140-146 (2016). WB . PubMed: 26889230