Anti-TCN1 antibody (ab202121)
Key features and details
- Rabbit polyclonal to TCN1
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-TCN1 antibody
See all TCN1 primary antibodies -
Description
Rabbit polyclonal to TCN1 -
Host species
Rabbit -
Tested applications
Suitable for: WB, ICC/IFmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length protein corresponding to Human TCN1 aa 1 to the C-terminus.
Database link: P20061 -
Positive control
- U2OS cells; BT474 and HT-29 cell lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab202121 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/2000. Predicted molecular weight: 48 kDa.
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ICC/IF |
Use at an assay dependent dilution.
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Notes |
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WB
1/500 - 1/2000. Predicted molecular weight: 48 kDa. |
ICC/IF
Use at an assay dependent dilution. |
Target
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Function
Vitamin B12-binding protein. Transports cobalamin into cells. -
Tissue specificity
Neutrophil granule protein. -
Sequence similarities
Belongs to the eukaryotic cobalamin transport proteins family. -
Post-translational
modificationsContains about 30% carbohydrates. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 6947 Human
- Omim: 189905 Human
- SwissProt: P20061 Human
- Unigene: 2012 Human
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Alternative names
- Haptocorin antibody
- Haptocorrin antibody
- HC antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (4)
ab202121 has been referenced in 4 publications.
- Hou X et al. 3D-SeboSkin Model for Human ex vivo Studies of Hidradenitis Suppurativa/Acne Inversa. Dermatology 238:236-243 (2022). PubMed: 34077928
- Zhu X et al. TCN1 Deficiency Inhibits the Malignancy of Colorectal Cancer Cells by Regulating the ITGB4 Pathway. Gut Liver N/A:N/A (2022). PubMed: 35686504
- Zhu X et al. Clinicopathological Analysis and Prognostic Assessment of Transcobalamin I (TCN1) in Patients with Colorectal Tumors. Med Sci Monit 26:e923828 (2020). PubMed: 32753569
- Zouboulis CC et al. Alterations in innate immunity and epithelial cell differentiation are the molecular pillars of hidradenitis suppurativa. J Eur Acad Dermatol Venereol 34:846-861 (2020). PubMed: 31838778