Anti-Thymosin beta 4 antibody (ab14335)
Key features and details
- Rabbit polyclonal to Thymosin beta 4
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Thymosin beta 4 antibody
See all Thymosin beta 4 primary antibodies -
Description
Rabbit polyclonal to Thymosin beta 4 -
Host species
Rabbit -
Specificity
Human Thymosin B4 (aa 1-11) -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to Human Thymosin beta 4 aa 1-11 conjugated to keyhole limpet haemocyanin.
Sequence:SDKPDMAEIEK
Database link: P62328 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Concentration information loading...
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Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab14335 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/100 - 1/1000.
Tested in lung and heart tissues. |
Notes |
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IHC-P
1/100 - 1/1000. Tested in lung and heart tissues. |
Target
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Function
Plays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
Seraspenide inhibits the entry of hematopoeitic pluripotent stem cells into the S-phase. -
Tissue specificity
Expressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells. -
Sequence similarities
Belongs to the thymosin beta family. -
Cellular localization
Cytoplasm > cytoskeleton. - Information by UniProt
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Database links
- Entrez Gene: 7114 Human
- Omim: 300159 Human
- SwissProt: P62328 Human
- Unigene: 437277 Human
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Alternative names
- Fx antibody
- Hematopoietic system regulatory peptide antibody
- Prothymosin beta 4 antibody
see all
Images
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Immunohistochemical analysis of adult rat testis tissue, staining Thymosin beta 10 with ab14335 at 1/1000 dilution.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human hear tissue sections labeling Thymosin beta 4 with ab14335 at 1/100 dilution, followed by an appropriate secondary antibody conjugated to Cy3. The nuclei were stained with DAPI.
Datasheets and documents
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Datasheet download
References (5)
ab14335 has been referenced in 5 publications.
- Mantri M et al. Spatiotemporal single-cell RNA sequencing of developing chicken hearts identifies interplay between cellular differentiation and morphogenesis. Nat Commun 12:1771 (2021). PubMed: 33741943
- Wong SW et al. H2O 2 Exposure Affects Myotube Stiffness and Actin Filament Polymerization. Ann Biomed Eng 43:1178-88 (2015). PubMed: 25371376
- Fu X et al. Thymosin ß4 promotes hepatoblastoma metastasis via the induction of epithelial-mesenchymal transition. Mol Med Rep 12:127-32 (2015). IHC ; Human . PubMed: 25695679
- Taverna D et al. Multiplexed molecular descriptors of pressure ulcers defined by imaging mass spectrometry. Wound Repair Regen 19:734-44 (2011). PubMed: 22092844
- Lagarrigue M et al. Revisiting Rat Spermatogenesis with MALDI Imaging at 20-{micro}m Resolution. Mol Cell Proteomics 10:M110.005991 (2011). IHC-P ; Rat . PubMed: 21149303