Anti-Tropomodulin 1 antibody (ab88608)
Key features and details
- Mouse polyclonal to Tropomodulin 1
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Tropomodulin 1 antibody
See all Tropomodulin 1 primary antibodies -
Description
Mouse polyclonal to Tropomodulin 1 -
Host species
Mouse -
Tested applications
Suitable for: WB, ICC/IFmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length protein within Human Tropomodulin 1. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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Positive control
- Human colon lysate, Tropomodulin 1 transfected 293T cell lysate, HeLa cells
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab88608 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 41 kDa.
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ICC/IF |
Use a concentration of 10 µg/ml.
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Notes |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 41 kDa. |
ICC/IF
Use a concentration of 10 µg/ml. |
Target
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Function
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus. -
Tissue specificity
Highly expressed in the erythrocyte, heart and skeletal muscle. -
Sequence similarities
Belongs to the tropomodulin family. -
Cellular localization
Cytoplasm > cytoskeleton. - Information by UniProt
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Database links
- Entrez Gene: 7111 Human
- Omim: 190930 Human
- SwissProt: P28289 Human
- Unigene: 404289 Human
- Unigene: 723236 Human
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Alternative names
- D9S57E antibody
- E Tmod antibody
- E tropomodulin antibody
see all
Images
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Anti-Tropomodulin 1 antibody (ab88608) at 1 µg/ml + Human colon lysate at 50 µg
Predicted band size: 41 kDa
Observed band size: 41 kDa -
All lanes : Anti-Tropomodulin 1 antibody (ab88608) at 1 µg/ml
Lane 1 : Tropomodulin 1 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Predicted band size: 41 kDa
Observed band size: 41 kDa -
ab88608 at 10µg/ml staining Tropomodulin 1 in HeLa cells by Immunofluorescence.
Protocols
Datasheets and documents
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Datasheet download
References (0)
ab88608 has not yet been referenced specifically in any publications.