Anti-Tropomodulin 2 antibody (ab67407)
Key features and details
- Mouse polyclonal to Tropomodulin 2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-Tropomodulin 2 antibody
See all Tropomodulin 2 primary antibodies -
Description
Mouse polyclonal to Tropomodulin 2 -
Host species
Mouse -
Specificity
ab67407 is reactive against mammalian transfected lysate -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length protein within Human Tropomodulin 2 aa 1-400. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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Positive control
- ICC: Murine Neuroblastoma (N1E-115) cells. WB: Tropomodulin 2 transfected 293T lysate, N1E-115 mouse neuroblastoma.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.4
Constituent: PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab67407 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | (2) |
1/500 - 1/1000. Detects a band of approximately 39.6 kDa.
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Notes |
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WB
1/500 - 1/1000. Detects a band of approximately 39.6 kDa. |
Target
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Relevance
Tropomodulin is the actin-capping protein for the slow growing end of filamentous actin. Tropomodulin 2 is a neuronal specific isoform which is the major binding protein to brain tropomyosin in rat. -
Cellular localization
Cytoplasm; cytoskeleton -
Database links
- Entrez Gene: 29767 Human
- Omim: 602928 Human
- SwissProt: Q9NZR1 Human
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Alternative names
- Tropomodulin 2 antibody
- MGC39481 antibody
- N Tmod antibody
see all
Images
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All lanes : Anti-Tropomodulin 2 antibody (ab67407) at 1/500 dilution
Lane 1 : Tropomodulin 2 transfected 293T lysate
Lane 2 : Non transfected 293T lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Observed band size: 39.6 kDa why is the actual band size different from the predicted? -
Lane 1 : Anti-Tropomodulin 2 antibody (ab67407) at 1/1000 dilution
Lane 2 : Anti-Tropomodulin 2 antibody [EPR6353] (ab124833) at 1/1000 dilution
All lanes : N1E-115 mouse neuroblastoma
Lysates/proteins at 20 µg per lane.
Secondary
All lanes : Polyclonal HRP conjugate at 1/5000 dilution
Datasheets and documents
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Datasheet download
References (4)
ab67407 has been referenced in 4 publications.
- Omotade OF et al. Tropomodulin Isoform-Specific Regulation of Dendrite Development and Synapse Formation. J Neurosci 38:10271-10285 (2018). PubMed: 30301754
- Gu QH et al. miR-26a and miR-384-5p are required for LTP maintenance and spine enlargement. Nat Commun 6:6789 (2015). PubMed: 25858512
- Hu Z et al. miR-191 and miR-135 are required for long-lasting spine remodelling associated with synaptic long-term depression. Nat Commun 5:3263 (2014). WB, ICC/IF . PubMed: 24535612
- Sun Y et al. A gel-based proteomic method reveals several protein pathway abnormalities in fetal Down syndrome brain. J Proteomics 74:547-57 (2011). WB ; Human . PubMed: 21262400