Yohimbine hydrochloride, alpha2 adrenoceptor antagonist (ab120239)
Key features and details
- Selective α2 adrenoceptor antagonist
- CAS Number: 65-19-0
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Pausinystalia yohimbe
Overview
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Product name
Yohimbine hydrochloride, alpha2 adrenoceptor antagonist -
Description
Selective α2 adrenoceptor antagonist -
CAS Number
65-19-0 -
Chemical structure
Properties
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Chemical name
(16α,17α)-17-Hydroxyyohimban-16-carboxylic acid methyl ester hydrochloride -
Molecular weight
390.91 -
Molecular formula
C21H26N2O3.HCl -
PubChem identifier
6169 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Cl.O=C(OC)[C@H]2[C@@H](O)CC[C@H]3CN4CCc1c5ccccc5nc1[C@@H]4C[C@H]23 -
Source
Pausinystalia yohimbe
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Research areas
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (3)
ab120239 has been referenced in 3 publications.
- Burke DA & Alvarez VA Serotonin receptors contribute to dopamine depression of lateral inhibition in the nucleus accumbens. Cell Rep 39:110795 (2022). PubMed: 35545050
- Yeung M et al. FG7142, yohimbine, and ßCCE produce anxiogenic-like effects in the elevated plus-maze but do not affect brainstem activated hippocampal theta. Neuropharmacology 75:47-52 (2013). PubMed: 23851259
- Meitzen J et al. ß1-Adrenergic receptors activate two distinct signaling pathways in striatal neurons. J Neurochem 116:984-95 (2011). PubMed: 21143600