Anti-ZDHHC13 antibody (ab28759)
Key features and details
- Goat polyclonal to ZDHHC13
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-ZDHHC13 antibody -
Description
Goat polyclonal to ZDHHC13 -
Host species
Goat -
Specificity
This antibody is expected to recognise both reported isoforms (as represented by NP_061901 and NP_001001483). -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide:
(C)FHPAREKVLRSV
, corresponding to C terminal amino acids 611-622 of Human ZDHHC13 Peptide is available as ab45682 - ZDHHC13 peptide (611-622) -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% Tris, 0.5% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
This antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab28759 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Notes |
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This antibody gave a positive result in ELISA against the immunizing peptide.
Antibody detection limit dilution 1:32,000.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
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Function
Palmitoyltransferase for HD and GAD2 (By similarity). Mediates Mg(2+) transport. -
Sequence similarities
Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
Contains 6 ANK repeats.
Contains 1 DHHC-type zinc finger. -
Domain
The DHHC domain is required for palmitoyltransferase activity. -
Cellular localization
Golgi apparatus membrane. Cytoplasmic vesicle membrane. Low extracellular Mg(2+) induces increase in Golgi and in post-Golgi vesicles. - Information by UniProt
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Database links
- Entrez Gene: 54503 Human
- Entrez Gene: 243983 Mouse
- Entrez Gene: 365252 Rat
- Omim: 612815 Human
- SwissProt: Q8IUH4 Human
- SwissProt: Q9CWU2 Mouse
- Unigene: 188569 Human
- Unigene: 279116 Mouse
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Alternative names
- DHHC 13 antibody
- DHHC-13 antibody
- FLJ10852 antibody
see all
Images
Datasheets and documents
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Datasheet download
References (2)
ab28759 has been referenced in 2 publications.
- Chen S et al. Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads. Nat Commun 10:877 (2019). PubMed: 30787281
- Chen S et al. Palmitoylation-dependent activation of MC1R prevents melanomagenesis. Nature 549:399-403 (2017). WB . PubMed: 28869973