Overview

  • Product name

    A 61603, alpha1A-adrenoceptor agonist
  • Description

    Potent, selective α1A-adrenoceptor agonist
  • Biological description

    Potent, selective α1A-adrenoceptor agonist. Increases spontaneous Ca2+ transients in myocytes (EC50 = 7 nM). Shows vasoconstrictive and hypertensive effects in vivo.
  • Purity

    > 99%
  • CAS Number

    107756-30-9
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Zimnik NC  et al. a(1A)-Adrenergic regulation of inhibition in the olfactory bulb. J Physiol 591:1631-43 (2013). Read more (PubMed: 23266935) »
  • Mori A  et al. Noradrenaline contracts rat retinal arterioles via stimulation of a(1A)- and a(1D)-adrenoceptors. Eur J Pharmacol 673:65-9 (2011). Read more (PubMed: 22040923) »
  • Knepper SM  et al. A-61603, a potent alpha 1-adrenergic receptor agonist, selective for the alpha 1A receptor subtype. J Pharmacol Exp Ther 274:97-103 (1995). Read more (PubMed: 7616455) »

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