Anti-A2BP1/Fox1/RBFOX1 antibody [1G10] (ab183348)
Key features and details
- Mouse monoclonal [1G10] to A2BP1/Fox1/RBFOX1
- Suitable for: ICC/IF, WB
- Reacts with: Rat
- Isotype: IgG1
Overview
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Product name
Anti-A2BP1/Fox1/RBFOX1 antibody [1G10]
See all A2BP1/Fox1/RBFOX1 primary antibodies -
Description
Mouse monoclonal [1G10] to A2BP1/Fox1/RBFOX1 -
Host species
Mouse -
Tested applications
Suitable for: ICC/IF, WBmore details -
Species reactivity
Reacts with: Rat -
Immunogen
Recombinant fragment corresponding to Human A2BP1/Fox1/RBFOX1 (N terminal). (Expressed in and purified from E.coli).
Database link: Q9NWB1 -
Positive control
- Rat cerebral cortex tissue lysate; Rat neurons (cultured).
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.065% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
1G10 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab183348 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ICC/IF |
1/500.
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WB |
1/5000. Detects a band of approximately 46, 48 kDa (predicted molecular weight: 42 kDa).
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Notes |
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ICC/IF
1/500. |
WB
1/5000. Detects a band of approximately 46, 48 kDa (predicted molecular weight: 42 kDa). |
Target
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Function
RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. -
Tissue specificity
Predominantly expressed in muscle and brain. -
Sequence similarities
Contains 1 RRM (RNA recognition motif) domain. -
Cellular localization
Nucleus. Cytoplasm. - Information by UniProt
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Database links
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Alternative names
- 2BP1 antibody
- A2 BP1 antibody
- A2BP 1 antibody
see all
Images
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Anti-A2BP1/Fox1/RBFOX1 antibody [1G10] (ab183348) at 1/5000 dilution + Rat cerebral cortex tissue lysate
Predicted band size: 42 kDa
Observed band size: 46-48 kDa why is the actual band size different from the predicted? -
Immunofluorescent analysis of cultured Rat neurons labeling A2BP1/Fox1/RBFOX1 with ab183348 at 1/500 dilution.
Protocols
Datasheets and documents
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Datasheet download
References (1)
ab183348 has been referenced in 1 publication.
- Kim EY et al. Distinct pathological signatures in human cellular models of myotonic dystrophy subtypes. JCI Insight 4:N/A (2019). PubMed: 30730308