Overview

  • Product name

    Anti-AARS2 antibody
  • Description

    Rabbit polyclonal to AARS2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Fusion protein corresponding to Human AARS2 (internal sequence). (BC131728).
    Database link: Q5JTZ9

  • Positive control

    • SP20 cell lysate; Human lymphoma tissue.
  • General notes

    Previously labelled as Alanyl-tRNA synthetase 2.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.30
    Preservative: 0.05% Sodium azide
    Constituents: 49% PBS, 50% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab197367 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/40 - 1/200.
WB 1/500 - 1/2000. Predicted molecular weight: 107 kDa.

Target

  • Relevance

    Alanyl-tRNA synthetase 2 (AARS2) is an enzyme that catalyzes the chemical reaction: ATP + L-alanine + tRNA(Ala) <---> AMP + diphosphate + L-alanyl-tRNA(Ala). This enzyme participates in alanine and aspartate metabolism and aminoacyl-tRNA biosynthesis.
  • Cellular localization

    Mitochondrion matrix
  • Database links

  • Alternative names

    • AARS 2 antibody
    • AARS2 antibody
    • AARSL antibody
    • Alanine tRNA ligase 2 mitochondrial antibody
    • Alanine tRNA ligase antibody
    • Alanyl tRNA synthetase 2 mitochondrial antibody
    • Alanyl tRNA synthetase like antibody
    • Alanyl-tRNA synthetase 2 antibody
    • AlaRS antibody
    • bA444E17.1 antibody
    • COXPD8 antibody
    • Gm89 antibody
    • KIAA1270 antibody
    • LKENP antibody
    • MGC69820 antibody
    • MT ALARS antibody
    • MTALARS antibody
    • Probable alanyl tRNA synthetase mitochondrial antibody
    • RP11-444E17.1 antibody
    see all

Images

  • Anti-AARS2 antibody (ab197367) at 1/600 dilution + SP20 cell lysate at 40 µg

    Developed using the ECL technique.

    Predicted band size: 107 kDa


    Exposure time: 15 seconds


    Gel: 8%SDS-PAGE

  • Immunohistochemical analysis of paraffin-embedded Human lymphoma tissue labeling AARS2 with ab197367 at 1/40 dilution.

References

This product has been referenced in:

  • Sommerville EW  et al. Instability of the mitochondrial alanyl-tRNA synthetase underlies fatal infantile-onset cardiomyopathy. Hum Mol Genet 28:258-268 (2019). Read more (PubMed: 30285085) »
See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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