Anti-SGLT1 antibody (ab240474)
Key features and details
- Goat polyclonal to SGLT1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-SGLT1 antibody
See all SGLT1 primary antibodies -
Description
Goat polyclonal to SGLT1 -
Host species
Goat -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to Human SGLT1 aa 550-650 (Cysteine residue). (NP_000334.1)
Database link: P13866 -
Positive control
- WB: Human kidney tissue lysate. IHC-P: Human small intestine tissue. IHC-Fr: Human kidney tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab240474 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
Use a concentration of 3 - 6 µg/ml.
Steamed antigen retrieval with citrate buffer pH 6. |
Notes |
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IHC-P
Use a concentration of 3 - 6 µg/ml. Steamed antigen retrieval with citrate buffer pH 6. |
Target
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Function
Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules. -
Tissue specificity
Expressed mainly in intestine and kidney. -
Involvement in disease
Congenital glucose/galactose malabsorption -
Sequence similarities
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. -
Post-translational
modificationsN-glycosylation is not necessary for the cotransporter function. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 6523 Human
- Omim: 182380 Human
- SwissProt: P13866 Human
- Unigene: 1964 Human
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Alternative names
- D22S675 antibody
- High affinity sodium glucose cotransporter 1 antibody
- High affinity sodium glucose cotransporter antibody
see all
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab240474 has not yet been referenced specifically in any publications.