Recombinant FITC Anti-EPCR/CD201 antibody [016] (ab275630)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- FITC Rabbit monoclonal [016] to EPCR/CD201
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: FITC. Ex: 493nm, Em: 528nm
Overview
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Product name
FITC Anti-EPCR/CD201 antibody [016]
See all EPCR/CD201 primary antibodies -
Description
FITC Rabbit monoclonal [016] to EPCR/CD201 -
Host species
Rabbit -
Conjugation
FITC. Ex: 493nm, Em: 528nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Recombinant fragment (His-tag) corresponding to Mouse EPCR/CD201 aa 1 to the C-terminus (extracellular). Including signal peptide.
Database link: Q64695 -
Positive control
- Flow Cyt: bEnd.3 cells.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Do Not Freeze. Store In the Dark. -
Storage buffer
Preservative: 0.09% Sodium azide
Constituent: 0.5% BSA -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
016 -
Isotype
IgG -
Research areas
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab275630 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
Flow Cyt |
Use at an assay dependent concentration.
5 μl/Test |
Notes |
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Flow Cyt
Use at an assay dependent concentration. 5 μl/Test |
Target
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Function
Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation. -
Tissue specificity
Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney. -
Post-translational
modificationsN-glycosylated.
A soluble form exists; probably released by a metalloprotease. Seems to have the same activity as the membrane-bound form. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 19124 Mouse
- SwissProt: Q64695 Mouse
- Unigene: 3243 Mouse
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Alternative names
- Activated protein C receptor antibody
- APC receptor antibody
- APCR antibody
see all
Images
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Flow cytometric analysis of bEnd.3 (mouse brain endothelialpolyoma middle T antigen transformed cell line) cells labeling EPCR/CD201 with ab275630 at 5 μl/Test (black) compared with isotype control (Grey). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab275630 has not yet been referenced specifically in any publications.