Recombinant APC Anti-MARCKS (phospho S167 + S170) antibody [MARCKSS167170-C9] (ab278786)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- APC Rabbit monoclonal [MARCKSS167170-C9] to MARCKS (phospho S167 + S170)
- Suitable for: Flow Cyt
- Reacts with: Rat
- Conjugation: APC. Ex: 645nm, Em: 660nm
Related conjugates and formulations
Overview
-
Product name
APC Anti-MARCKS (phospho S167 + S170) antibody [MARCKSS167170-C9]
See all MARCKS primary antibodies -
Description
APC Rabbit monoclonal [MARCKSS167170-C9] to MARCKS (phospho S167 + S170) -
Host species
Rabbit -
Conjugation
APC. Ex: 645nm, Em: 660nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Rat
Predicted to work with: Human -
Immunogen
Synthetic peptide within Human MARCKS (phospho S167 + S170). The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: P29966 -
Positive control
- Flow cyt: C6 cells treated with UV+TPA.
-
General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Store In the Dark. -
Storage buffer
Preservative: 0.09% Sodium azide
Constituents: 99.71% PBS, 0.2% BSA -
Concentration information loading...
-
Purity
Protein A/G purified -
Clonality
Monoclonal -
Clone number
MARCKSS167170-C9 -
Isotype
IgG -
Light chain type
kappa -
Research areas
Associated products
-
Alternative Versions
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab278786 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
Flow Cyt |
Use 5µl for 106 cells.
|
Notes |
---|
Flow Cyt
Use 5µl for 106 cells. |
Target
-
Function
MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein. -
Sequence similarities
Belongs to the MARCKS family. -
Post-translational
modificationsPhosphorylation by PKC displaces MARCKS from the membrane. It also inhibits the F-actin cross-linking activity. -
Cellular localization
Cytoplasm > cytoskeleton. Membrane. - Information by UniProt
-
Database links
- Entrez Gene: 4082 Human
- Entrez Gene: 25603 Rat
- Omim: 177061 Human
- SwissProt: P29966 Human
- SwissProt: P30009 Rat
- Unigene: 519909 Human
- Unigene: 712721 Human
- Unigene: 9560 Rat
-
Alternative names
- 80 kDa protein antibody
- 80K L antibody
- 80K L protein antibody
see all
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
-
Datasheet download
References (0)
ab278786 has not yet been referenced specifically in any publications.