PF-3758309 (ab287116)
Key features and details
- A potent small molecule inhibitor of PAK4
- CAS Number: 898044-15-0
- Purity: >= 98%
Soluble to in DMSO to 10 mM
- Form / State: Solid
Overview
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Product name
PF-3758309 -
Description
A potent small molecule inhibitor of PAK4 -
Alternative names
- 898044-15-0
- UNII-PK459EA5I2
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Biological description
A potent small molecule inhibitor of p21-activated kinase 4 (PAK4) with potential antineoplastic activity. It binds to PAK4, inhibiting PAK4 activity and cancer cell growth. PAK4, a serine/threonine kinase belonging to the p21-activated kinase (PAK) family, is often upregulated in a variety of cancer cell types and plays an important role in cancer cell motility, proliferation, and survival.
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Purity
>= 98% -
General notes
This product is manufactured by BioVision, an Abcam company and was previously called B2634 PF-3758309. B2634-25 is the same size as the 25 mg size of ab287116.
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CAS Number
898044-15-0
Properties
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Chemical name
N-[(1S)-2-(dimethylamino)-1-phenylethyl]-6,6-dimethyl-3-[(2-methylthieno[3,2-d]pyrimidin-4-yl)amino]-1,4-dihydropyrrolo[3,4-c]pyrazole-5-carboxamide
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Molecular weight
490.60 -
Molecular formula
C25H30N8OS -
PubChem identifier
25227462 -
Storage instructions
Shipped at 4°C. Store at -20°C long term. Store In the Dark. -
Solubility overview
Soluble to in DMSO to 10 mM
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Handling
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=NC2=C(C(=N1)NC3=NNC4=C3CN(C4(C)C)C(=O)NC(CN(C)C)C5=CC=CC=C5)SC=C2 -
Research areas
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Cholesterol Metabolism
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Fatty acids
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Energy transfer pathways
- Energy Metabolism
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab287116 has not yet been referenced specifically in any publications.