Active RHEB peptide (ab39862)
Key features and details
- Active: Yes
- Suitable for: Blocking
Description
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Product name
Active RHEB peptide
See all RHEB proteins and peptides -
Biological activity
This peptide is used for blocking the activity of the Anti-Rheb antibody (ab25976). -
Animal free
No -
Nature
Synthetic
Specifications
Our Abpromise guarantee covers the use of ab39862 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Blocking
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Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% BSAThis product is an active protein and may elicit a biological response in vivo, handle with caution.
General Info
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Alternative names
- Ras homolog enriched in brain 2, formerly
- GTP binding protein Rheb
- GTP-binding protein Rheb
see all -
Function
Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Activates the protein kinase activity of mTORC1. Has low intrinsic GTPase activity. -
Tissue specificity
Ubiquitous. Highest levels observed in skeletal and cardiac muscle. -
Sequence similarities
Belongs to the small GTPase superfamily. Rheb family. -
Post-translational
modificationsFarnesylation is important for efficiently activating mTORC1-mediated signaling. -
Cellular localization
Cell membrane. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab39862 has not yet been referenced specifically in any publications.