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    abca6-antibody-ab180567.pdf

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Cardiovascular Lipids / Lipoproteins Lipid Metabolism Cholesterol Metabolism
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Anti-ABCA6 antibody (ab180567)

  • Datasheet
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Western blot - Anti-ABCA6 antibody (ab180567)

    Key features and details

    • Rabbit polyclonal to ABCA6
    • Suitable for: WB
    • Reacts with: Mouse, Rat, Human
    • Isotype: IgG

    You may also be interested in

    Secondary
    Product image
    Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

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    Overview

    • Product name

      Anti-ABCA6 antibody
      See all ABCA6 primary antibodies
    • Description

      Rabbit polyclonal to ABCA6
    • Host species

      Rabbit
    • Tested applications

      Suitable for: WBmore details
    • Species reactivity

      Reacts with: Mouse, Rat, Human
    • Immunogen

      Recombinant full length protein corresponding to Mouse ABCA6 aa 1-1624.
      Sequence:

      MKELSVHVRQQTRALLHKILLKKWRRKRESLLEWSIPIIIGLHMGLFSYL ARNIQVLEVPPQDLGSLNEFNGSSLVVVYTPISNITQQIMNKTTFAPTMK GTRIIGVPSIEDLEVLLHNIPDALGVIFNDSFSYQLKVLRMYGNPFLKED LLAHCWDTHSQAFCSLSKYWERGFVALQTAINAGIIEVTTNHSVMEELMS IDGINMKTLPFIPRDLSDYEIFILFCLLYFSSFIYFASSNVTKERKQCKE VMKVMGLQDSAFWLSWGLIYVGFIFIISIFIAIIITSTQIIMMTGFLVIF TLFFLYGLSLIAVTFLMAVLLQKAVLTNLIVLFFTLFWGCVGFTVLHKEL PPSLEWVLSIFSPFAFTSGMAKVIFQDYNLNGVVFPDPSGESYVMIAVFF ILAFDSLLYLVLALYFDKILLYGAEHRSAPLFFLNPTSCFRKTANRNKVI ERDLDPELPSDEYFEPVDPEYQGKEAIRIRNIKKEYKGKSGKVKALKGLF LDIYESQITAILGHSGAGKSSLLNILSGLYVPTAGSVTVYNKNLSDMQDL KEIRKAIGVCPQHNVQFDALTVKENLTLFAKIKGILPQDVEQEVQQILS ELDMQNIRDDLAEHLSEGQKRKLTFGIATVGDPQILLLDEPTVGLDPFS RQRIWGFLKERRADHVILFSTQFMDEADILADRKVLIANGALKCTGSSVF LKRKWGLGYHLSLFMDETCDSERLTSFINHHIPYAKLKAKTKEKLVYILP LERTSEFPEFFSDLDKYSGQGLMSYEVSMSTLNDVFLNLEGEPSTKQDFE KRETATDSESLNDMEVAYPSLSQVQETVSTMSLWRMQVCAIARLRILKLK RERKAFLIILLLLGIALLPLVIEYVANALLEVKNNWEFKTDLYFLSPGQL PQGLRTSLLVINNTESNIEDFLQSLKHQNIVLEVDDFENRNATNSLSYNG AIIVSGRQKDY RFSAVCNTKRLHCFPILMNVISNGILHMLNHTQYIRI KEDIFSPFIVLVWTGIQETCLFILCVICSLSPHIAMSSVSDYKKKADSQL WISGLYPSAYWCGQAVVDISLFSGMLLTSYFTSYTSKLLNIDMTSEIVFS VIVLALGCAASLVFLTYVISFVFGKRKKNSTLWSICFLLVIAITFEKVAN GPFNEALVISATMLVPSFALNGLLVVLEMRAYQYYIEFEEIKHGLSAVDL LLCLIPYIHTLLFIFVLRCLELKYGKNVVRRDPIFRIAPQSLKAQPNPEE PIDEDENVQAERLRTSDALSTPNLDEKPVIIASCLHKEYAGQKKHCCSRR TRNMAVRNVSFCVNKGEILGLLGPDGAGKSSSIRMIAGITKPTAGQVELK RLSSAVGHQGDSRAEFGYCPQENGLWPNLTVKEHLELYAAVKGLRKEDAV VAISRLVNALKLHDQLNVQVQNLVAGATRKLCFVLSILGNSPV LILDE PSTGLDVSGKHQVWQAIQAVVKDNEKGVLLSTHDLAEAEALCDRAAIMVS GRLRCIGPIQHLKRKFGQDYVLELRVKDVSQEPLVHREILKLFPQAARQD RCFSLLTYKLPVTDVHPLSQAFHKLEAVKHGFDLEDYSLSQCTLDRVILE LSKEQELGTVYEEADMTLGRKLLPPSDEL


      Database link: Q8K441
      Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
    • General notes

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    Properties

    • Form

      Liquid
    • Storage instructions

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
    • Storage buffer

      pH: 7.30
      Preservative: 0.02% Sodium azide
      Constituents: 49% PBS, 50% Glycerol
    • Concentration information loading...
    • Purity

      Immunogen affinity purified
    • Clonality

      Polyclonal
    • Isotype

      IgG
    • Research areas

      • Cardiovascular
      • Lipids / Lipoproteins
      • Lipid Metabolism
      • Cholesterol Metabolism
      • Signal Transduction
      • Metabolism
      • Lipid metabolism
      • Metabolism
      • Pathways and Processes
      • Metabolic signaling pathways
      • Lipid and lipoprotein metabolism
      • Cholesterol Metabolism

    Associated products

    • Compatible Secondaries

      • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
      • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
    • Isotype control

      • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)

    Applications

    Our Abpromise guarantee covers the use of ab180567 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    WB 1/500 - 1/2000. Predicted molecular weight: 183 kDa.

    Target

    • Function

      Probable transporter which may play a role in macrophage lipid homeostasis.
    • Tissue specificity

      Widely expressed with higher expression in liver.
    • Sequence similarities

      Belongs to the ABC transporter superfamily. ABCA family.
      Contains 2 ABC transporter domains.
    • Developmental stage

      Expressed in fetal kidney, lung and liver.
    • Cellular localization

      Membrane.
    • Target information above from: UniProt accession Q8N139 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links

      • Entrez Gene: 23460 Human
      • Entrez Gene: 76184 Mouse
      • Entrez Gene: 303639 Rat
      • Omim: 612504 Human
      • SwissProt: Q8N139 Human
      • SwissProt: Q8K441 Mouse
      • Unigene: 709514 Human
      • Unigene: 159704 Mouse
      • Alternative names

        • ABC transporter ABCA6 antibody
        • ABCA 6 antibody
        • ABCA6 antibody
        • ABCA6_HUMAN antibody
        • ATP binding cassette A6 antibody
        • ATP binding cassette sub family A (ABC1) member 6 antibody
        • ATP binding cassette sub family A member 6 antibody
        • ATP-binding cassette sub-family A member 6 antibody
        • EST155051 antibody
        • FLJ43498 antibody
        see all

      Images

      • Western blot - Anti-ABCA6 antibody (ab180567)
        Western blot - Anti-ABCA6 antibody (ab180567)
        Anti-ABCA6 antibody (ab180567) at 1/500 dilution + 293T cell extract

        Predicted band size: 183 kDa

      Protocols

      • Western blot protocols

      Click here to view the general protocols

      Datasheets and documents

      • Datasheet
    • References (1)

      Publishing research using ab180567? Please let us know so that we can cite the reference in this datasheet.

      ab180567 has been referenced in 1 publication.

      • Imperio GE  et al. Gestational age-dependent gene expression profiling of ATP-binding cassette transporters in the healthy human placenta. J Cell Mol Med 23:610-618 (2019). PubMed: 30407748

      Customer reviews and Q&As

      Show All Reviews Q&A
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      There are currently no Customer reviews or Questions for ab180567.
      Please use the links above to contact us or submit feedback about this product.

      Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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