Overview

  • Product name

  • Description

    Rabbit polyclonal to ABCA8
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human ABCA8 (internal sequence) conjugated to keyhole limpet haemocyanin.
    Database link: O94911

  • Positive control

    • WB: HEK-293T and RAW 264.7 whole cell lysates; rat kidney lysate. IHC-P: Human brain cortex tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab230896 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 179 kDa.
IHC-P 1/100.

Target

  • Relevance

    ABCA8 is a member of the superfamily of ATP binding cassette (ABC) transporters. ABC proteins transport various molecules across extra and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The function of this protein has not yet been determined.
  • Cellular localization

    Cell membrane; Multi pass membrane protein
  • Database links

  • Alternative names

    • ABCA 8 antibody
    • ATP binding cassette sub family A member 8 antibody
    • ATP binding cassette, sub family A (ABC1), member 8 antibody

Images

  • All lanes : Anti-ABCA8 antibody (ab230896) at 1/500 dilution

    Lane 1 : HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate
    Lane 2 : RAW 264.7 (mouse macrophage cell line transformed with Abelson murine leukemia virus) whole cell lysate
    Lane 3 : Rat kidney lysate

    Predicted band size: 179 kDa

  • Formalin-fixed, paraffin-embedded human brain cortex tissue stained for ABCA8 using ab230896 at 1/100 dilution in immunohistochemical analysis.

References

ab230896 has not yet been referenced specifically in any publications.

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