Overview

  • Product name

  • Description

    Rabbit polyclonal to ABCB6/PRP
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, ELISA, WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Human ABCB6/PRP aa 440-455 (internal sequence).
    Sequence:

    RAMNTQENATRARAVD

  • Positive control

    • KB cells transfected with the ABCB6/PRP protein.
  • General notes

     This product was previously labelled as ABCB6

     

Properties

Applications

Our Abpromise guarantee covers the use of ab47837 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF
ELISA
WB
  • Application notes
    ELISA: 1/40000 - 1/200000.
    IF (microscopy): Use at an assay dependent dilution.
    WB: 1/1000 - 1/5000. Predicted molecular weight: 93 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function

      Binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis.
    • Tissue specificity

      Widely expressed. Highest expression in heart and skeletal muscles.
    • Sequence similarities

      Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
      Contains 1 ABC transmembrane type-1 domain.
      Contains 1 ABC transporter domain.
    • Developmental stage

      Highly expressed in fetal liver.
    • Cellular localization

      Mitochondrion outer membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • ABC antibody
      • ABC transporter umat antibody
      • ABC14 antibody
      • Abcb6 antibody
      • ABCB6_HUMAN antibody
      • ATP binding cassette sub family B member 6, mitochondrial precursor antibody
      • ATP binding cassette, sub family B (MDR/TAP), member 6 antibody
      • ATP-binding cassette half-transporter antibody
      • ATP-binding cassette sub-family B member 6 antibody
      • ATP-binding cassette sub-family B member 6, mitochondrial antibody
      • DUH3 antibody
      • LAN antibody
      • MCOPCB7 antibody
      • Mitochondrial ABC transporter 3 antibody
      • mitochondrial antibody
      • Mt ABC transporter 3 antibody
      • Mt-ABC transporter 3 antibody
      • MTABC3 antibody
      • P glycoprotein related protein antibody
      • P-glycoprotein-related protein antibody
      • PRP antibody
      • Ubiquitously expressed mammalian ABC half transporter antibody
      • Ubiquitously-expressed mammalian ABC half transporter antibody
      • UMAT antibody
      see all

    Images

    • All lanes : Anti-ABCB6/PRP antibody (ab47837) at 1/1400 dilution

      Lane 1 : KB cell lysate expressing Flag™-tagged human ABCB6/PRP protein
      Lane 2 : KB cell lysate without a vector insert

      Predicted band size: 93 kDa
      Observed band size: 104 kDa
      why is the actual band size different from the predicted?
      Additional bands at: 79 kDa (possible truncated form)

    References

    ab47837 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab47837.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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