Anti-ABCB6/PRP antibody - C-terminal (ab194409)
Key features and details
- Mouse polyclonal to ABCB6/PRP - C-terminal
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Overview
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Product name
Anti-ABCB6/PRP antibody - C-terminal
See all ABCB6/PRP primary antibodies -
Description
Mouse polyclonal to ABCB6/PRP - C-terminal -
Host species
Mouse -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Recombinant fragment (GST-tag) corresponding to Human ABCB6/PRP aa 700 to the C-terminus (C terminal). NP_005680
Database link: Q9NP58 -
Positive control
- HeLa, RAW264.7, PC-12 and NIH3T3 cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Constituent: 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab194409 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/2500. Predicted molecular weight: 94 kDa.
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Notes |
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WB
1/500 - 1/2500. Predicted molecular weight: 94 kDa. |
Target
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Function
Binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis. -
Tissue specificity
Widely expressed. Highest expression in heart and skeletal muscles. -
Sequence similarities
Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
Contains 1 ABC transmembrane type-1 domain.
Contains 1 ABC transporter domain. -
Developmental stage
Highly expressed in fetal liver. -
Cellular localization
Mitochondrion outer membrane. - Information by UniProt
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Database links
- Entrez Gene: 10058 Human
- Entrez Gene: 74104 Mouse
- Entrez Gene: 140669 Rat
- Omim: 605452 Human
- SwissProt: Q9NP58 Human
- SwissProt: Q9DC29 Mouse
- SwissProt: O70595 Rat
- Unigene: 107911 Human
see all -
Alternative names
- ABC antibody
- ABC transporter umat antibody
- ABC14 antibody
see all
Images
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Anti-ABCB6/PRP antibody - C-terminal (ab194409) at 1/500 dilution + NIH3T3 cell lysate at 50 µg
Secondary
Goat Anti-Mouse IgG at 1/2500 dilution
Predicted band size: 94 kDa -
Anti-ABCB6/PRP antibody - C-terminal (ab194409) at 1/500 dilution + RAW264.7 cell lysate at 50 µg
Secondary
Goat Anti-Mouse IgG at 1/2500 dilution
Predicted band size: 94 kDa -
Anti-ABCB6/PRP antibody - C-terminal (ab194409) at 1/500 dilution + PC-12 cell lysate at 50 µg
Secondary
Goat Anti-Mouse IgG at 1/2500 dilution
Predicted band size: 94 kDa -
Anti-ABCB6/PRP antibody - C-terminal (ab194409) at 1/500 dilution + HeLa cell lysate at 50 µg
Secondary
Goat Anti-Mouse IgG at 1/2500 dilution
Predicted band size: 94 kDa
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab194409 has been referenced in 1 publication.
- Morton AB et al. Mitochondrial accumulation of doxorubicin in cardiac and diaphragm muscle following exercise preconditioning. Mitochondrion N/A:N/A (2018). WB ; Rat . PubMed: 29474837