Overview

  • Product name

    Anti-ABCB6/PRP antibody - C-terminal
    See all ABCB6/PRP primary antibodies
  • Description

    Mouse polyclonal to ABCB6/PRP - C-terminal
  • Host species

    Mouse
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant fragment (GST-tag) corresponding to Human ABCB6/PRP aa 743-842 (C terminal). NP_005680
    Sequence:

    KAPGIILLDEATSALDTSNERAIQASLAKVCANRTTIVVAHRLSTVVNAD QILVIKDGCIVERGRHEALLSRGGVYADMWQLQQGQEETSEDTKPQTMER


    Database link: Q9NP58

  • Positive control

    • HeLa, RAW264.7, PC-12 and NIH3T3 cell lysate.
  • General notes

     This product was previously labelled as ABCB6

     

Properties

Applications

Our Abpromise guarantee covers the use of ab194409 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2500. Predicted molecular weight: 94 kDa.

Target

  • Function

    Binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis.
  • Tissue specificity

    Widely expressed. Highest expression in heart and skeletal muscles.
  • Sequence similarities

    Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
    Contains 1 ABC transmembrane type-1 domain.
    Contains 1 ABC transporter domain.
  • Developmental stage

    Highly expressed in fetal liver.
  • Cellular localization

    Mitochondrion outer membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • ABC antibody
    • ABC transporter umat antibody
    • ABC14 antibody
    • Abcb6 antibody
    • ABCB6_HUMAN antibody
    • ATP binding cassette sub family B member 6, mitochondrial precursor antibody
    • ATP binding cassette, sub family B (MDR/TAP), member 6 antibody
    • ATP-binding cassette half-transporter antibody
    • ATP-binding cassette sub-family B member 6 antibody
    • ATP-binding cassette sub-family B member 6, mitochondrial antibody
    • DUH3 antibody
    • LAN antibody
    • MCOPCB7 antibody
    • Mitochondrial ABC transporter 3 antibody
    • mitochondrial antibody
    • Mt ABC transporter 3 antibody
    • Mt-ABC transporter 3 antibody
    • MTABC3 antibody
    • P glycoprotein related protein antibody
    • P-glycoprotein-related protein antibody
    • PRP antibody
    • Ubiquitously expressed mammalian ABC half transporter antibody
    • Ubiquitously-expressed mammalian ABC half transporter antibody
    • UMAT antibody
    see all

Images

  • Anti-ABCB6/PRP antibody - C-terminal (ab194409) at 1/500 dilution + NIH3T3 cell lysate at 50 µg

    Secondary
    Goat Anti-Mouse IgG at 1/2500 dilution

    Predicted band size: 94 kDa

  • Anti-ABCB6/PRP antibody - C-terminal (ab194409) at 1/500 dilution + RAW264.7 cell lysate at 50 µg

    Secondary
    Goat Anti-Mouse IgG at 1/2500 dilution

    Predicted band size: 94 kDa

  • Anti-ABCB6/PRP antibody - C-terminal (ab194409) at 1/500 dilution + PC-12 cell lysate at 50 µg

    Secondary
    Goat Anti-Mouse IgG at 1/2500 dilution

    Predicted band size: 94 kDa

  • Anti-ABCB6/PRP antibody - C-terminal (ab194409) at 1/500 dilution + HeLa cell lysate at 50 µg

    Secondary
    Goat Anti-Mouse IgG at 1/2500 dilution

    Predicted band size: 94 kDa

References

This product has been referenced in:

  • Morton AB  et al. Mitochondrial accumulation of doxorubicin in cardiac and diaphragm muscle following exercise preconditioning. Mitochondrion N/A:N/A (2018). WB ; Rat . Read more (PubMed: 29474837) »
See 1 Publication for this product

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