Key features and details
- Rabbit polyclonal to ABCB7
- Suitable for: IHC-P, ELISA
- Reacts with: Human
- Isotype: IgG
Product nameAnti-ABCB7 antibody
See all ABCB7 primary antibodies
DescriptionRabbit polyclonal to ABCB7
SpecificityThis antibody reacts with ABCB7
Tested applicationsSuitable for: IHC-P, ELISAmore details
Species reactivityReacts with: Human
Synthetic peptide corresponding to Human ABCB7 aa 733-747 conjugated to Keyhole Limpet Haemocyanin (KLH).
- Thymus tissue
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.1% Sodium azide
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab65149 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 10 µg/ml.|
|ELISA||1/10 - 1/1000.|
FunctionCould be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins.
Involvement in diseaseDefects in ABCB7 are the cause of X-linked sideroblastic anemia with ataxia (ASAT) [MIM:301310]. ASAT is a recessive disorder characterized by an infantile to early childhood onset of nonprogressive cerebellar ataxia and mild anemia with hypochromia and microcytosis.
Sequence similaritiesBelongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
Contains 1 ABC transmembrane type-1 domain.
Contains 1 ABC transporter domain.
Cellular localizationMitochondrion inner membrane.
- Information by UniProt
- ABC transporter 7 protein antibody
- ABC7 antibody
- Abcb7 antibody
ab65149 has been referenced in 1 publication.
- Nikpour M et al. The transporter ABCB7 is a mediator of the phenotype of acquired refractory anemia with ring sideroblasts. Leukemia 27:889-896 (2013). PubMed: 23070040