Overview

  • Product name

  • Description

    Rabbit polyclonal to ABCC10
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human ABCC10 aa 835-884. The exact sequence is proprietary.
    Database link: Q5T3U5

  • Positive control

    • IHC-P: Human kidney tissue. WB: COLO 205 and COS-7 cell extracts.

Properties

Applications

Our Abpromise guarantee covers the use of ab230917 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
WB 1/500 - 1/1000. Predicted molecular weight: 161 kDa.

Target

  • Function

    ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion.
  • Tissue specificity

    Isoform 1 is specifically expressed in spleen. Isoform 2 is more widely expressed.
  • Sequence similarities

    Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
    Contains 2 ABC transmembrane type-1 domains.
    Contains 2 ABC transporter domains.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • ABCC10 antibody
    • ATP binding cassette, sub family C (CFTR/MRP), member 10 antibody
    • ATP binding cassette, subfamily C, member 10 antibody
    • ATP-binding cassette sub-family C member 10 antibody
    • EST182763 antibody
    • mFLJ00002 antibody
    • MRP7 antibody
    • MRP7_HUMAN antibody
    • Multidrug resistance associated protein 7 antibody
    • Multidrug resistance-associated protein 7 antibody
    • SIMRP7 antibody
    see all

Images

  • All lanes : Anti-ABCC10 antibody (ab230917) at 1/500 dilution

    Lane 1 : COLO 205 (Human colon adenocarcinoma cell line) cell extracts
    Lane 2 : COS-7 (African green monkey kidney fibroblast-like cell line) cell extracts
    Lane 3 : COLO 205 cell extracts with immunizing peptide

    Predicted band size: 161 kDa

  • Formalin-fixed, paraffin-embedded human kidney tissue stained for ABCC10 using ab230917 at 1/50 dilution in immunohistochemical analysis.

References

ab230917 has not yet been referenced specifically in any publications.

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