Anti-ABCC12 antibody [M9I-38] (ab91453)
Key features and details
- Rat monoclonal [M9I-38] to ABCC12
- Suitable for: IHC-Fr, ICC, WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-ABCC12 antibody [M9I-38] -
Description
Rat monoclonal [M9I-38] to ABCC12 -
Host species
Rat -
Tested applications
Suitable for: IHC-Fr, ICC, WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment within Human ABCC12 aa 1-100 (N terminal). The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.3
Preservative: 0.1% Sodium azide
Constituent: 0.7% BSA
Tissue culture supernatant (Serum free) -
Concentration information loading...
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Purity
Tissue culture supernatant -
Clonality
Monoclonal -
Clone number
M9I-38 -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab91453 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-Fr |
Use at an assay dependent concentration.
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ICC |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration.
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Notes |
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IHC-Fr
Use at an assay dependent concentration. |
ICC
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
Target
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Function
Probable transporter. -
Tissue specificity
Expressed in testis (at protein level). Widely expressed at low level. Isoform 5 is specifically expressed in brain, testis and breast cancer cells. -
Sequence similarities
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Contains 2 ABC transmembrane type-1 domains.
Contains 2 ABC transporter domains. -
Developmental stage
Expressed in fetal tissues. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 94160 Human
- Omim: 607041 Human
- SwissProt: Q96J65 Human
- Unigene: 410111 Human
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Alternative names
- 4930467B22Rik antibody
- ABCC 12 antibody
- Abcc12 antibody
see all
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab91453 has been referenced in 3 publications.
- Wei W et al. The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1. Oncol Res 28:423-438 (2020). PubMed: 32331534
- Shi B et al. Effect of sodium butyrate on ABC transporters in lung cancer A549 and colorectal cancer HCT116 cells. Oncol Lett 20:148 (2020). PubMed: 32934716
- Wang H et al. Effects of histone deacetylase inhibitors on ATP-binding cassette transporters in lung cancer A549 and colorectal cancer HCT116 cells. Oncol Lett 18:63-71 (2019). PubMed: 31289473