Overview

  • Product name

  • Description

    Rabbit polyclonal to ABCF1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 1-192 of Human ABCF1.

  • Positive control

    • 293T whole cell lysate; Human hepatoma tissue; HeLa cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab126260 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 95 kDa.
IHC-P 1/100 - 1/1000.
ICC/IF 1/100 - 1/1000.

Target

  • Function

    Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis.
  • Tissue specificity

    Ubiquitous.
  • Sequence similarities

    Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
    Contains 2 ABC transporter domains.
  • Post-translational
    modifications

    Isoform 2 is phosphorylated at phosphoserine and phosphothreonine. Isoform 2 phosphorylation on Ser-109 and Ser-140 by CK2; inhibits association of EIF2 with ribosomes.
  • Cellular localization

    Cytoplasm. Nucleus, nucleoplasm. Nucleus envelope.
  • Information by UniProt
  • Database links

  • Alternative names

    • ABC27 antibody
    • ABC50 antibody
    • ABCF1 antibody
    • ABCF1_HUMAN antibody
    • ATP binding cassette 50 (TNF alpha stimulated) antibody
    • ATP binding cassette 50 antibody
    • ATP binding cassette sub family F member 1 antibody
    • ATP binding cassette, sub family F (GCN20), member 1 antibody
    • ATP-binding cassette 50 antibody
    • ATP-binding cassette sub-family F member 1 antibody
    • AU041969 antibody
    • D17Wsu166e antibody
    • EST123147 antibody
    • GCN20 antibody
    • TNF alpha stimulated ABC protein antibody
    • TNF-alpha-stimulated ABC protein antibody
    • TNFalpha inducible ATP binding protein antibody
    • wu:fb79c06 antibody
    • wu:fc39a05 antibody
    • wu:fj94a08 antibody
    • zgc:85667 antibody
    see all

Images

  • Anti-ABCF1 antibody (ab126260) at 1/3000 dilution + 293T whole cell lysate at 30 µg

    Predicted band size: 95 kDa



    5% SDS-PAGE
  • ab126260 at 1/500 dilution staining ABCF1 in paraformaldehyde-fixed HeLa cells by Immunofluorescence(green). Alpha tubulin filaments were labelled red.
  • ab126260 at 1/500 staining ABCF1 in paraffin embedded Human hepatoma tissue by Immunohistochemistry.

References

ab126260 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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