Anti-ABCG1 antibody (ab217023)

Submit a review Submit a question

Key features and details

  • Rabbit polyclonal to ABCG1
  • Suitable for: IHC-P
  • Reacts with: Human
  • Isotype: IgG

Overview

  • Product name

    Anti-ABCG1 antibody
    See all ABCG1 primary antibodies

  • Description

    Rabbit polyclonal to ABCG1

  • Host species

    Rabbit

  • Tested applications

    Suitable for: IHC-Pmore details

  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat

  • Immunogen

    Synthetic peptide within Human ABCG1 aa 640-678 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    ELDVENAKLYL DFIVLGIFFI SLRLIAYFVL RYKIRAER


    Database link: P45844

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • Positive control

    • Human placenta tissue.

  • General notes

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Applications

Our Abpromise guarantee covers the use of ab217023 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.

Target

  • Function

    Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages.

  • Tissue specificity

    Expressed in several tissues. Expressed in macrophages; expression is increased in macrophages from patients with Tangier disease.

  • Sequence similarities

    Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
    Contains 1 ABC transmembrane type-2 domain.
    Contains 1 ABC transporter domain.

  • Cellular localization

    Endoplasmic reticulum membrane. Golgi apparatus membrane. Predominantly localized in the intracellular compartments mainly associated with the endoplasmic reticulum (ER) and Golgi membranes.
  • Information by UniProt

  • Database links

    see all

  • Alternative names

    • ABC transporter 8 antibody
    • ABC8 antibody
    • ABCG1 antibody
    • ABCG1_HUMAN antibody
    • ATP-binding cassette sub family G member 1 antibody
    • ATP-binding cassette sub-family G member 1 antibody
    • ATP-binding cassette transporter 8 antibody
    • ATP-binding cassette transporter member 1 of subfamily G antibody
    • ATP-binding cassette, sub family G WHITE member 1 antibody
    • homolog of Drosophila white antibody
    • MGC34313 antibody
    • White protein homolog antibody
    • White protein homolog ATP binding cassette transporter 8 antibody
    • WHITE1 antibody
    • WHT1 antibody
    see all

Images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ABCG1 antibody (ab217023)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ABCG1 antibody (ab217023)

    Immunohistochemical analysis of formalin-fixed and paraffin embedded human placenta tissue labeling ABCG1 with ab217023 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.

References (0)

Publishing research using ab217023? Please let us know so that we can cite the reference in this datasheet.

ab217023 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Show All Reviews Q&A
Submit a review Submit a question

There are currently no Customer reviews or Questions for ab217023.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com