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  1. Link

    abcg1-antibody-ab217023.pdf

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Neuroscience Cell Type Marker Glia marker Astrocyte marker
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Anti-ABCG1 antibody (ab217023)

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  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ABCG1 antibody (ab217023)

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Primary

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Secondary

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Protein

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  • Datasheet
  • References
  • Protocols

Overview

  • Product name

    Anti-ABCG1 antibody
    See all ABCG1 primary antibodies
  • Description

    Rabbit polyclonal to ABCG1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide within Human ABCG1 aa 640-678 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    ELDVENAKLYL DFIVLGIFFI SLRLIAYFVL RYKIRAER


    Database link: P45844

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive control

    • Human placenta tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituents: 50% Glycerol, 1% BSA
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Neuroscience
    • Cell Type Marker
    • Glia marker
    • Astrocyte marker
    • Cardiovascular
    • Lipids / Lipoproteins
    • Lipid Metabolism
    • Cholesterol Metabolism
    • Cardiovascular
    • Lipids / Lipoproteins
    • Lipoproteins/Apolipoproteins
    • Signal Transduction
    • Metabolism
    • Lipid metabolism
    • Cardiovascular
    • Atherosclerosis
    • Lipoprotein metabolism
    • Cardiovascular
    • Atherosclerosis
    • Lipid transport
    • Cancer
    • Cancer Metabolism
    • Metabolic signaling pathway
    • Metabolism of lipids and lipoproteins
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Lipid metabolism
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Cholesterol Metabolism
    • Metabolism
    • Pathways and Processes
    • Metabolic signaling pathways
    • Lipid and lipoprotein metabolism
    • Lipoprotein metabolism
    • Metabolism
    • Types of disease
    • Heart disease

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
  • Recombinant Protein

    • Recombinant Human ABCG1 protein (ab153003)
  • Related Products

    • Recombinant Human ABCG1 protein (ab153003)

Applications

Our Abpromise guarantee covers the use of ab217023 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.

Target

  • Function

    Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages.
  • Tissue specificity

    Expressed in several tissues. Expressed in macrophages; expression is increased in macrophages from patients with Tangier disease.
  • Sequence similarities

    Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
    Contains 1 ABC transmembrane type-2 domain.
    Contains 1 ABC transporter domain.
  • Cellular localization

    Endoplasmic reticulum membrane. Golgi apparatus membrane. Predominantly localized in the intracellular compartments mainly associated with the endoplasmic reticulum (ER) and Golgi membranes.
  • Target information above from: UniProt accession P45844 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 9619 Human
    • Entrez Gene: 11307 Mouse
    • Entrez Gene: 85264 Rat
    • Omim: 603076 Human
    • SwissProt: P45844 Human
    • SwissProt: Q64343 Mouse
    • Unigene: 124649 Human
    • Unigene: 15691 Mouse
    • Unigene: 470747 Mouse
    • Unigene: 8398 Rat
    see all
  • Alternative names

    • ABC transporter 8 antibody
    • ABC8 antibody
    • ABCG1 antibody
    • ABCG1_HUMAN antibody
    • ATP-binding cassette sub family G member 1 antibody
    • ATP-binding cassette sub-family G member 1 antibody
    • ATP-binding cassette transporter 8 antibody
    • ATP-binding cassette transporter member 1 of subfamily G antibody
    • ATP-binding cassette, sub family G WHITE member 1 antibody
    • homolog of Drosophila white antibody
    • MGC34313 antibody
    • White protein homolog antibody
    • White protein homolog ATP binding cassette transporter 8 antibody
    • WHITE1 antibody
    • WHT1 antibody
    see all

Images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ABCG1 antibody (ab217023)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ABCG1 antibody (ab217023)

    Immunohistochemical analysis of formalin-fixed and paraffin embedded human placenta tissue labeling ABCG1 with ab217023 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.

Protocols

  • Immunohistochemistry protocols

Datasheets and documents

    • Datasheet
  • References

    ab217023 has not yet been referenced specifically in any publications.

    Publishing research using ab217023? Please let us know so that we can cite the reference in this datasheet.

    Customer reviews and Q&As

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