ABT-751 (E-7010), Antimitotic agent (ab142973)
Key features and details
- Antimitotic agent. Microtubule polymerization inhibitor.
- CAS Number: 141430-65-1
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 25 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
ABT-751 (E-7010), Antimitotic agent -
Description
Antimitotic agent. Microtubule polymerization inhibitor. -
Alternative names
- E-7010
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Biological description
Antimitotic agent. Microtubule polymerization inhibitor. Induces G2M phase cell cycle arrest and apoptosis. Disrupts tumor vasculature. Shows antitumor effects in vivo. Orally active. -
Purity
> 99% -
CAS Number
141430-65-1 -
Chemical structure
Properties
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Chemical name
N-[2-(4-Hydroxyanilino)pyridin-3-yl]-4-methoxybenzenesulfonamide -
Molecular weight
371.41 -
Molecular formula
C18H17N3O4S -
PubChem identifier
3035714 -
Storage instructions
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 25 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
COC1=CC=C(C=C1)S(=O)(=O)NC2=C(N=CC=C2)NC3=CC=C(C=C3)O -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab142973 has not yet been referenced specifically in any publications.
