Key features and details
- Rabbit polyclonal to AC3
- Suitable for: WB, ICC/IF, IHC-FrFl
- Reacts with: Rat, Human
- Isotype: IgG
Product nameAnti-AC3 antibody
See all AC3 primary antibodies
DescriptionRabbit polyclonal to AC3
Tested applicationsSuitable for: WB, ICC/IF, IHC-FrFlmore details
Species reactivityReacts with: Rat, Human
Predicted to work with: Mouse, Chinese hamster
- Rat olfactory epithelium and frontal cortex lysates; Mixed neuron-glial cultures.
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We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferConstituent: PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab125093 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/5000 - 1/10000. Detects a band of approximately 160-200 kDa (predicted molecular weight: 129 kDa).|
|ICC/IF||1/500 - 1/1000.|
FunctionMediates odorant detection (possibly) via modulation of intracellular cAMP concentration.
Tissue specificityExpressed in brain, heart, kidney, liver, lung, pancreas, placenta, and skeletal muscle.
Sequence similaritiesBelongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Contains 2 guanylate cyclase domains.
- Information by UniProt
- AC-III antibody
- AC3 antibody
- ADCY3 antibody
Free foating immunohistochemistry of rat hippocampus stained with ab125093 at 1/10000 staining AC3 (red). A mouse antibody staining MECP2 (green), DNA is revealed with DAPI (blue).
ab125093, at 1/500, staining AC3 in mixed neuron-glial cultures by Immunofluorescence (red). A mouse monoclonal antibody staining of aII-spectrin (green) is also shown.
All lanes : Anti-AC3 antibody (ab125093) at 1/5000 dilution
Lane 1 : Rat olfactory epithelium lysate
Lane 2 : Rat frontal cortex lysate
Predicted band size: 129 kDa
ab125093 has been referenced in 2 publications.
- Frasca A et al. MECP2 mutations affect ciliogenesis: a novel perspective for Rett syndrome and related disorders. EMBO Mol Med 12:e10270 (2020). PubMed: 32383329
- Huang TW et al. Chitosan-hyaluronan: promotion of mucociliary differentiation of respiratory epithelial cells and development of olfactory receptor neurons. Artif Cells Nanomed Biotechnol 47:564-570 (2019). PubMed: 30857434