Overview

  • Product name

  • Description

    Rabbit polyclonal to AC3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IP, WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Dog, Human
  • Immunogen

    Synthetic peptide. This information is considered to be commercially sensitive.

Properties

Applications

Our Abpromise guarantee covers the use of ab14778 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at an assay dependent dilution. Use 5 ul for 2 x 107 cells.
WB 1/500. Detects a band of approximately 119 kDa (predicted molecular weight: 129 kDa).

Target

  • Function

    Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration.
  • Tissue specificity

    Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, and skeletal muscle.
  • Sequence similarities

    Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    Contains 2 guanylate cyclase domains.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • AC-III antibody
    • AC3 antibody
    • ADCY3 antibody
    • ADCY3_HUMAN antibody
    • adenylate cyclase 3 antibody
    • Adenylate cyclase antibody
    • Adenylate cyclase type 3 antibody
    • Adenylate cyclase type III antibody
    • Adenylyl cyclase 3 antibody
    • ATP pyrophosphate lyase antibody
    • ATP pyrophosphate-lyase 3 antibody
    • olfactive type antibody
    see all

References

This product has been referenced in:

  • Hong SH  et al. Upregulation of adenylate cyclase 3 (ADCY3) increases the tumorigenic potential of cells by activating the CREB pathway. Oncotarget 4:1791-803 (2013). Read more (PubMed: 24113161) »
  • Griffin CA  et al. MOR23 promotes muscle regeneration and regulates cell adhesion and migration. Dev Cell 17:649-61 (2009). WB ; Mouse . Read more (PubMed: 19922870) »
See all 3 Publications for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab14778.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up