Overview

  • Product name

  • Description

    Rabbit polyclonal to ACADM/MCAD
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Rat ACADM/MCAD.

  • Positive control

    • Rat kidney tissue lysate.
  • General notes

    Previously labelled as ACADM. 

Properties

Applications

Our Abpromise guarantee covers the use of ab129420 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 4 µg/ml. Predicted molecular weight: 47 kDa.

Target

  • Function

    This enzyme is specific for acyl chain lengths of 4 to 16.
  • Pathway

    Lipid metabolism; mitochondrial fatty acid beta-oxidation.
  • Involvement in disease

    Defects in ACADM are the cause of acyl-CoA dehydrogenase medium-chain deficiency (ACADMD) [MIM:201450]. It is an autosomal recessive disease which causes fasting hypoglycemia, hepatic dysfunction, and encephalopathy, often resulting in death in infancy.
  • Sequence similarities

    Belongs to the acyl-CoA dehydrogenase family.
  • Cellular localization

    Mitochondrion matrix.
  • Information by UniProt
  • Database links

  • Alternative names

    • ACAD 1 antibody
    • ACAD1 antibody
    • Acadm antibody
    • ACADM_HUMAN antibody
    • Acyl coenzyme A dehydrogenase antibody
    • Acyl coenzyme A dehydrogenase C 4 to C 12 straight chain antibody
    • FLJ18227 antibody
    • FLJ93013 antibody
    • FLJ99884 antibody
    • MCAD antibody
    • MCADH antibody
    • Medium chain acyl CoA dehydrogenase antibody
    • Medium chain fatty acyl CoA dehydrogenase antibody
    • Medium chain specific acyl CoA dehydrogenase antibody
    • Medium chain specific acyl CoA dehydrogenase mitochondrial antibody
    • Medium-chain specific acyl-CoA dehydrogenase antibody
    • mitochondrial antibody
    see all

Images

  • Anti-ACADM/MCAD antibody (ab129420) at 4 µg/ml + Rat kidney tissue lysate

    Predicted band size: 47 kDa

References

This product has been referenced in:

  • Zidek LM  et al. Deficiency in mTORC1-controlled C/EBPß-mRNA translation improves metabolic health in mice. EMBO Rep 16:1022-36 (2015). WB . Read more (PubMed: 26113365) »
See 1 Publication for this product

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