Overview

  • Product name

  • Description

    Rabbit polyclonal to ACADS/SCAD
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    Recombinant fragment corresponding to Human ACADS/SCAD aa 1-94.
    Database link: P16219

  • Positive control

    • HeLa S3, HepG2 and MOLT4 whole cell lysates; Human liver tissue.
  • General notes

    Previously labelled as ACADS. 

Applications

Our Abpromise guarantee covers the use of ab152100 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 44 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Pathway

    Lipid metabolism; mitochondrial fatty acid beta-oxidation.
  • Involvement in disease

    Defects in ACADS are the cause of acyl-CoA dehydrogenase short-chain deficiency (ACADSD) [MIM:201470]. It is an autosomal recessive disorder resulting in acute acidosis and muscle weakness in infants, and a form of lipid-storage myopathy in adults.
  • Sequence similarities

    Belongs to the acyl-CoA dehydrogenase family.
  • Cellular localization

    Mitochondrion matrix.
  • Information by UniProt
  • Database links

  • Alternative names

    • ACAD3 antibody
    • ACADS antibody
    • ACADS_HUMAN antibody
    • Acyl Coenzyme A dehydrogenase, C2 to C3 short chain antibody
    • Acyl-CoA dehydrogenase, C2 to C3 short chain antibody
    • Acyl-CoA dehydrogenase, short chain antibody
    • Acyl-Coenzyme A dehydrogenase, short chain antibody
    • AI196007 antibody
    • Bcd-1 antibody
    • Bcd1 antibody
    • Butyryl CoA dehydrogenase antibody
    • Butyryl-CoA dehydrogenase antibody
    • EC 1.3.99.2 antibody
    • mitochondrial antibody
    • SCAD antibody
    • Short chain acyl CoA dehydrogenase antibody
    • Short-chain specific acyl-CoA dehydrogenase antibody
    • Short-chain specific acyl-CoA dehydrogenase, mitochondrial antibody
    • Unsaturated acyl CoA reductase antibody
    see all

Images

  • Anti-ACADS/SCAD antibody (ab152100) at 1/500 dilution + MOLT4 whole cell
    lysate at 30 µg

    Predicted band size: 44 kDa



    12% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded Human liver tissue labeling ACADS  / SCAD with ab152100 at 10µg/ml.

References

ab152100 has not yet been referenced specifically in any publications.

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