Acedoben, para-aminobenzoic acid derivative (ab145067)

Overview

  • Product name

    Acedoben, para-aminobenzoic acid derivative
  • Description

    Acetylated derivative of para-aminobenzoic acid (PABA).
  • Alternative names

    • 4-(Acetylamino)benzoic Acid
    • 4-Acetamidobenzoic Acid
    • 4’-Carboxyacetanilide
    • N-Acetyl-p-aminobenzoic Acid
    • NSC 4002
    • p-(Acetylamino)benzoic Acid
    • p-Acetamidobenzoic Acid
    • p-Acetaminobenzoic Acid
    see all
  • Biological description

    Acetylated derivative of p-aminobenzoic acid (PABA). Metabolite of the anesthetic benzocaine (ab145835).

  • CAS Number

    556-08-1
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-(Acetylamino)benzoic acid
  • Molecular weight

    179.17
  • Molecular formula

    C9H9NO3
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Solubility overview

    DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Song DJ  et al. Metabolic kinetics of p-aminobenzoic acid in rabbits. Biopharm Drug Dispos 20:263-70 (1999). Read more (PubMed: 10594871) »
  • Barbieri B  et al. p-Aminobenzoic acid and its metabolite p-acetamidobenzoic acid inhibit agonist-induced aggregation and arachidonic acid-induced [Ca2+]i transients in human platelets. Thromb Res 95:235-43 (1999). Read more (PubMed: 10515288) »
  • Barbieri B  et al. p-Aminobenzoic acid, but not its metabolite p-acetamidobenzoic acid, inhibits thrombin induced thromboxane formation in human platelets in a non NSAID like manner. Thromb Res 86:127-40 (1997). Read more (PubMed: 9175234) »

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